S
Simon Champ
Publications - 5
Citations - 324
Simon Champ is an academic researcher. The author has contributed to research in topics: Lycopene & Prostate cancer. The author has an hindex of 5, co-authored 5 publications receiving 292 citations.
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Journal ArticleDOI
The Potential Role of Lycopene for the Prevention and Therapy of Prostate Cancer: From Molecular Mechanisms to Clinical Evidence
Nina Pauline Holzapfel,Boris Michael Holzapfel,Simon Champ,Jesper Feldthusen,Judith A. Clements,Dietmar W. Hutmacher +5 more
TL;DR: The potential impact of lycopene on prostate cancer by giving an overview about its molecular mechanisms and clinical effects is discussed in this paper, but there is still no clearly proven clinical evidence supporting the use of Lycopene in the prevention or treatment of prostate cancer, due to the only limited number of published randomized clinical trials and the varying quality of existing studies.
The potential role of lycopene for the prevention and therapy of prostate cancer : from molecular mechanisms to clinical evidence
Nina Pauline Holzapfel,Boris Michael Holzapfel,Simon Champ,Jesper Feldthusen,Judith A. Clements,Dietmar W. Hutmacher +5 more
TL;DR: The scope of this article is to discuss the potential impact of lycopene on prostate cancer by giving an overview about its molecular mechanisms and clinical effects.
Journal Article
Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load
Nina Pauline Holzapfel,Ali Shokoohmand,Ali Shokoohmand,Ferdinand Wagner,Ferdinand Wagner,Marietta Landgraf,Simon Champ,Boris Michael Holzapfel,Boris Michael Holzapfel,Judith A. Clements,Judith A. Clements,Dietmar W. Hutmacher,Daniela Loessner +12 more
TL;DR: The findings indicate that lycopene interferes with mechanisms involved in the development and progression of ovarian cancer and that its preventive and therapeutic use, combined with chemotherapeutics, reduces the tumor and metastatic burden of ovariancancer in vivo.
Journal ArticleDOI
Advanced tissue sciences inc.: learning from the past, a case study for regenerative medicine
TL;DR: In this paper, a case study of Advanced Tissue Sciences (ATS) liquidation is presented, with the effect that in excess of US$300 million of stakeholder financing was destroyed.
Journal ArticleDOI
Lycopene's Effects on Cancer Cell Functions within Monolayer and Spheroid Cultures.
Nina Pauline Holzapfel,Boris Michael Holzapfel,Christina Theodoropoulos,Elke Kaemmerer,Tamara Rausch,Jesper Feldthusen,Simon Champ,Judith A. Clements,Dietmar W. Hutmacher,Daniela Loessner +9 more
TL;DR: This study cannot substantiate that lycopene inhibits cell functions associated with tumor growth, even in a 3D cancer model that mimics the natural tumor microenvironment.