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Simon Descamps
Researcher at University of Rennes
Publications - 4
Citations - 285
Simon Descamps is an academic researcher from University of Rennes. The author has contributed to research in topics: Centrosome & Aurora B kinase. The author has an hindex of 3, co-authored 4 publications receiving 274 citations.
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On the role of aurora-A in centrosome function.
TL;DR: This review focuses on aurora-A that starts to localize to centrosomes only in S phase as soon as centrioles have been duplicated, the protein is then degraded in early G1, indicating that the kinase is an oncogene.
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Preparation and characterization of a human aurora-A kinase monoclonal antibody
TL;DR: Characterization of the 35C1 antibody revealed that it was able to immunoprecipitate the kinase, that it did not inhibit the aurora-A kinase activity and consequently could be used to measure the aur Nora-A Kinase activity in vivo after immunop Recipitation.
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Two mammalian mitotic aurora kinases: who's who?
Simon Descamps,Claude Prigent +1 more
TL;DR: The Perspective by Descamps and Prigent delves into the latest observations on aurora kinases in humans and the specific roles of each kinase within the process of mitosis.
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Aurora-A, -B et -C : À l’aube d’une nouvelle connexion entre l’amplification des centrosomes, l’aneuploïdie et le cancer ?
Simon Descamps,Claude Prigent +1 more
TL;DR: Une mitose anormale produit des cellules aneuploides contenant un nombre anormal de centrosomes, deux caracteres qui sont devenus des signatures de cellules tumorales, d’un genome parfaitement diploide.