Simonetta Ronca-Testoni

TL;DR: The ryanodine receptor (RyR)c corresponds to the sarcoplasmic reticulum (SR) Ca2+ channel and its structure and function have been reviewed recently.

TL;DR: The discovery of 3-iodothyronamine (T1AM), a naturally occurring derivative of TH that in vitro is a potent agonist of the G protein–coupled trace amine receptor TAR1, suggests the existence of a new signaling pathway, stimulation of which leads to rapid physiological and behavioral consequences that are opposite those associated with excess TH.

TL;DR: The findings provide evidence for the existence of a novel aminergic system modulating cardiac function and 3‐iodothyronamine T1AM is a novel endogenous thyroid hormone derivative that activates the G protein‐coupled receptor known as trace anime‐associated receptor 1 (TAAR1).

TL;DR: Fasting did not produce significant changes in ghrelin gene expression, while the distribution of gh Relin between different tissues was significantly modified: protein concentration increased in the brain, cerebellum, lung and salivary gland, while it decreased in the stomach.

TL;DR: It is concluded that ghrelin and hexarelin have a specific cardioprotective effect, which is independent of growth hormone secretion, and might be related to protein kinase C activation.