S
Sivaraj Saranya
Researcher at Department of Biotechnology
Publications - 5
Citations - 147
Sivaraj Saranya is an academic researcher from Department of Biotechnology. The author has contributed to research in topics: Isatin & Crystal structure. The author has an hindex of 4, co-authored 5 publications receiving 102 citations. Previous affiliations of Sivaraj Saranya include University Health Network.
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Journal ArticleDOI
Isatin based thiosemicarbazone derivatives as potential bioactive agents: Anti-oxidant and molecular docking studies
Jebiti Haribabu,Govindarajulu Rangabashyam Subhashree,Sivaraj Saranya,K. Gomathi,Ramasamy Karvembu,Dasararaju Gayathri +5 more
TL;DR: In this article, a series of isatin based thiosemicarbazones has been synthesized from benzylisatin and unsubstituted/substitution of thio-micarazone derivatives (1, 3 and 4).
Journal ArticleDOI
Synthesis, crystal structure, and in vitro and in silico molecular docking of novel acyl thiourea derivatives
Jebiti Haribabu,Govindarajulu Rangabashyam Subhashree,Sivaraj Saranya,K. Gomathi,Ramasamy Karvembu,Dasararaju Gayathri +5 more
TL;DR: In this paper, a series of six biologically active substituted acyl thiourea compounds ( 1 - 6 ) has been synthesized from cyclohexanecarbonyl isothiocyanate and various primary amines.
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In vitro antioxidant, antiinflammatory and in silico molecular docking studies of thiosemicarbazones
Govindarajulu Rangabashyam Subhashree,Jebiti Haribabu,Sivaraj Saranya,Panneerselvam Yuvaraj,D. Anantha Krishnan,Ramasamy Karvembu,Dasararaju Gayathri +6 more
TL;DR: A series of 5-methoxysalicylaldehyde/2-hydroxy-1-naphthaldehyde and (un)substituted thiosemicarbazides with the view to ascertain their biological properties brought about by the change in substitution at the N-terminal position of the derivatives were fully characterized by elemental analyses, and various spectroscopic techniques (UV-Visible, FT-IR, NMR and mass).
Journal ArticleDOI
Molecular structures, Hirshfeld analysis and biological investigations of isatin based thiosemicarbazones
Sivaraj Saranya,Jebiti Haribabu,Jebiti Haribabu,Vishnunarayanan Namboothiri Vadakkedathu Palakkeezhillam,P. Jerome,K. Gomathi,Kodagala Kameswara Rao,Velakaturi Hari Hara Surendra Babu,Ramasamy Karvembu,Dasararaju Gayathri +9 more
TL;DR: In this paper, the synthesized isatin thiosemicarbazone compounds (1, 10) were well characterized by elemental analysis, and UV-Visible, FT-IR and NMR spectroscopic methods.
Journal ArticleDOI
Effective inhibition of insulin amyloid fibril aggregation by nickel(II) complexes containing heterocyclic thiosemicarbazones
K. Gomathi,Jebiti Haribabu,Sivaraj Saranya,Dasararaju Gayathri,Kumaramangalam Jeyalakshmi,Kumaramangalam Jeyalakshmi,Subramanian Sendilvelan,Cesar Echeverria,Ramasamy Karvembu +8 more
TL;DR: In this article, the effect of nickel(II) complexes (N1, N2, N3, and N4) bearing thiosemicarbazones on the inhibition of amyloid fibril formation by insulin was investigated.