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Sobhi M. Gomha

Researcher at Islamic University

Publications -  227
Citations -  4385

Sobhi M. Gomha is an academic researcher from Islamic University. The author has contributed to research in topics: Thiazole & Chemistry. The author has an hindex of 30, co-authored 197 publications receiving 2994 citations. Previous affiliations of Sobhi M. Gomha include Cairo University.

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Journal Article

Synthesis and anticancer activities of thiazoles, 1,3-thiazines, and thiazolidine using chitosan-grafted-poly (vinylpyridine) as basic catalyst

TL;DR: A series of thiazoles (III and (V), 1,3-thiazines (IX), and thiazolidine (VII) was prepared in the presence of an environmentally friendly basic chitosan-grafted poly(vinylpyridine) catalyst as discussed by the authors.
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Synthesis, characterization, and pharmacological evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as anticancer agents

TL;DR: In this paper, two series of novel 2-methyl-1-phenyl-5-substituted-1H-pyrazol-4-yl)ethylidene]hydrazono]-hydrazine-carbodithioate and thiosemicarbazide derivatives were prepared from reaction of hydrazonoyl halides with methyl 2-[1-(5-methyl]-1-phenyl-1,phenyl]-1,phexane]-hexane derivatives, respectively.
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A convenient ultrasound-promoted synthesis of some new thiazole derivatives bearing a coumarin nucleus and their cytotoxic activity.

TL;DR: The cytototoxic activities of the thiazole derivative 5a was evaluated against HaCaT cells (human keratinocytes) and it was found that compound 5a possess potent cytotoxic activity.
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Synthesis and anticancer activity of arylazothiazoles and 1,3,4-thiadiazoles using chitosan-grafted-poly(4-vinylpyridine) as a novel copolymer basic catalyst

TL;DR: In this paper, a series of 4-substituted 5-arylazo-2-[1-(pyrrol-3-yl)ethylidenehydrazinyl]-2,3-dihydrothiazol-3amines was prepared by cyclocondensation of α-oxohydrazonoyl halides with 1-(pyl-3yl)-ethylidenethiosemicarbazide and 1-(polyvinylpyridine), respectively.
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Synthesis under microwave irradiation of [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazoles and other diazoles bearing indole moieties and their antimicrobial evaluation.

TL;DR: Microwave-assisted synthesis of some novel compounds, namely, 3-(2-methyl-1H-indol-3-yl)-6-aryl[1,2,4]triazolo[3,4-b][1,3, 4]thiadiazoles 5a,b was accomplished via bromination of 2- methyl-3-[4-(arylideneamino)-5-mercapto-4H-[1, 2,4