Soichiro Shimizu

TL;DR: MIBG myocardial scintigraphy may improve the sensitivity in the detection ofDLB and provide a powerful differential diagnostic tool when it is difficult to distinguish cases of DLB from AD using brain perfusion SPECT.

TL;DR: T2*-weighted gradient-echo magnetic resonance imaging (MRI) scans were obtained to determine the frequency, extent, and pattern of MBs in patients with Alzheimer’s disease (AD), and MBs were defined on gradient- echo T2*weighted images as homogenous rounded lesions of signal loss with a diameter greater than 2 mm.

TL;DR: Subjects with AD, even the early stages of AD, showed a high prevalence rate of sarcopenia and there were differences in muscle functions and physical performance between the stages of the female and male AD.

TL;DR: Combined studies of MMSE and brain SPECT achieved a high discrimination between DLB and AD with a sensitivity of 81% and a specificity of 85%, suggesting that there is a useful and practical approach to differentiate DLB from AD.

TL;DR: Comparing regional cerebral blood flow patterns in patients with dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD) using single photon emission computed tomography (SPECT) and investigating the diagnostic utility of SPECT study in differentiating between DLB and AD revealed that Objective and quantitative CBF measurement in the medial occipital lobe may be useful in the clinical differentiation of DLB.