S
Sona Lyndem
Researcher at National Institute of Technology, Meghalaya
Publications - 8
Citations - 280
Sona Lyndem is an academic researcher from National Institute of Technology, Meghalaya. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 1, co-authored 2 publications receiving 175 citations.
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An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study.
TL;DR: Rutin ( a natural compound) has the highest inhibitor efficiency among the 33 molecules studied, followed by ritonavir (control drug), emetine (anti-protozoal), hesperidin (a natural compound), lopinavir ( control drug) and indinavir(anti-viral drug).
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Interaction Properties of Biosynthesized Cadmium Sulphide Quantum Dots with Human Serum Albumin: Further Investigation of Antibacterial Activities and Sensing Applications.
TL;DR: The biosynthesized biogenic cadmium sulphide QDs were found to have extensive antibacterial activity against both gram-negative E. coli and gram-positive E. faecalis bacterial strains and showed highly effective sensors for tetracycline, rifampicin and bilirubin.
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Binding of bioactive esculin and esculetin with hen egg white lysozyme: Spectroscopic and computational methods to comprehensively elucidate the binding affinities, interacting forces, and conformational alterations at molecular level
TL;DR: In this paper , the binding constants of esculin and esculetin with hen egg white lysozyme (HEWL) were investigated using multi-spectroscopic and computational methods.
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A comprehensive in vitro exploration into the interaction mechanism of coumarin derivatives with bovine hemoglobin: Spectroscopic and computational methods
Sona Lyndem,Upasana Hazarika,P. Athul,Anindita Bhatta,Vivek Prakash,Anupam Nath Jha,Atanu Singha Roy +6 more
TL;DR: In this article , the binding of coumarin derivatives with bovine hemoglobin was investigated using various biophysical and computational techniques and the binding constant was found moderate in nature.
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Molecular recognition of two bioactive coumarin derivatives 7-hydroxycoumarin and 4-methyl-7-hydroxycoumarin by hen egg white lysozyme: Exploring the binding mechanism, thermodynamic parameters and structural changes using multispectroscopic and computational approaches.
TL;DR: In this paper, multispectroscopic and computational methods of exploring the interaction between a carrier protein and therapeutic compounds provide a preliminary investigation into establishing the efficacy of s t -drugs.