S
Soo-Hyun Kim
Researcher at Catholic University of Korea
Publications - 12
Citations - 347
Soo-Hyun Kim is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Metastasis & Breast cancer. The author has an hindex of 10, co-authored 12 publications receiving 286 citations. Previous affiliations of Soo-Hyun Kim include University of Melbourne & Peter MacCallum Cancer Centre.
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Journal ArticleDOI
Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice.
TL;DR: The advantages and limitations of using genetically engineered immunodeficient mouse models, patient-derived xenografts (PDXs), and humanized mouse models for developing and testing immunotherapeutic strategies are discussed.
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[10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo.
Ana Carolina Baptista Moreno Martin,Angelina M. Fuzer,Amanda Blanque Becceneri,James Almada da Silva,Rebeka Tomasin,Delphine Denoyer,Soo-Hyun Kim,Katherine A. McIntyre,Helen B. Pearson,Belinda Yeo,Aadya Nagpal,Xiawei Ling,Heloisa S. Selistre-de-Araujo,Paulo C. Vieira,Márcia Regina Cominetti,Normand Pouliot,Normand Pouliot +16 more
TL;DR: Results indicate that [10]-gingerol may be a safe and useful complementary therapy for the treatment of metastatic breast cancer and warrant further investigation of its efficacy, either alone or in combination with standard systemic therapies, in pre-clinical models of metastasis, in patients and in patients.
Journal ArticleDOI
Neurotrophic activity of DA-9801, a mixture extract of Dioscorea japonica Thunb. and Dioscorea nipponica Makino, in vitro.
Nam Ho Kim,Soo-Hyun Kim,Yu Jin Kim,Jeong-Ki Kim,Min-Kyung Nam,Hyangshuk Rhim,Sungjoo Kim Yoon,Sang-Zin Choi,Miwon Son,Sun Yeou Kim,Hyo-Jeong Kuh +10 more
TL;DR: The NGF agonistic activity of DA- 9801 and DA-9801E was demonstrated, which may contribute to their neuroprotective effect against diabetic peripheral neuropathy (DPN).
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Tumour but not stromal expression of β3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer.
Rachel Zoe Carter,Kelli Cristina Micocci,Anthony Natoli,Richard P. Redvers,Sophie Paquet-Fifield,Ana Carolina Baptista Moreno Martin,Delphine Denoyer,Xiawei Ling,Soo-Hyun Kim,Soo-Hyun Kim,Rebeka Tomasin,Heloisa S. Selistre-de-Araujo,Robin L. Anderson,Robin L. Anderson,Normand Pouliot,Normand Pouliot +15 more
TL;DR: It is concluded that tumour, rather than stromal, β3 expression is essential and is required early for efficient spontaneous breast cancer metastasis to bone and soft tissues, and it is proposed that β3 inhibitors may be more efficacious if used in a neoadjuvant setting,rather than after metastases are established.
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Anti-tumor activity of noble indirubin derivatives in human solid tumor models in vitro.
TL;DR: The data suggest that compounds 11 and 33 may exert a significant anti-solid tumor activity via a mechanism other than CDK inhibition, different from that of 4c and 4l.