S
Stanislav S. Rubakhin
Researcher at University of Illinois at Urbana–Champaign
Publications - 146
Citations - 6211
Stanislav S. Rubakhin is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Mass spectrometry & Mass spectrometry imaging. The author has an hindex of 43, co-authored 134 publications receiving 5437 citations. Previous affiliations of Stanislav S. Rubakhin include Icahn School of Medicine at Mount Sinai & Urbana University.
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Profiling metabolites and peptides in single cells
TL;DR: Established and evolving strategies for characterizing the metabolome and peptidome of single cells are highlighted to provide a greater understanding of cell fate, function and homeostatic balance.
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MALDI-MS imaging of features smaller than the size of the laser beam.
TL;DR: The presented MS imaging technique enables ∼25 µm imaging spatial resolution using commercial MALDI mass spectrometers having irregular laser beam sizes of several hundred micron diameters and with appropriate sampling, the size of the laser beam is not a strict barrier to the attainable MalDI-MS imaging resolution.
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Imaging mass spectrometry : fundamentals and applications to drug discovery
TL;DR: The fundamentals and unique methodology of IMS are discussed, along with exciting new applications to drug discovery science.
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Capillary electrophoresis with electrospray ionization mass spectrometric detection for single-cell metabolomics.
TL;DR: A method that enables metabolomic profiling of single cells and subcellular structures is described using capillary electrophoresis coupled to electrospray ionization time-of-flight mass spectrometry and demonstrated with identified neurons from Aplysia californica.
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Mass spectrometry imaging and profiling of single cells.
TL;DR: Advances in ion probe technologies have increased the dynamic range and sensitivity of analyte detection by SIMS, allowing two- and three-dimensional localization of analytes in a variety of cells, and other approaches for MS-based chemical imaging and profiling include those based on near-field laser ablation and inductively-coupled plasma MS analysis, which offer complementary capabilities.