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Stefan Hülsmann
Researcher at Schering AG
Publications - 3
Citations - 181
Stefan Hülsmann is an academic researcher from Schering AG. The author has contributed to research in topics: Glass transition & Solubility. The author has an hindex of 2, co-authored 3 publications receiving 176 citations.
Papers
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Journal ArticleDOI
Melt extrusion – an alternative method for enhancing the dissolution rate of 17β-estradiol hemihydrate
TL;DR: The method of choice in this study, melt extrusion, proved to overcome many of the shortcomings of conventional methods and achieve a significant increase in dissolution rate when compared to the pure drug or to the physical mixtures.
Journal ArticleDOI
Stability of Extruded 17β-Estradiol Solid Dispersions
TL;DR: In this paper, different analytical methods were applied showing that no recrystallization occurred after treating melt extruded solid dispersions with 17β-Estradiol as the model drug with heat or water vapor.
Patent
Pharmazeutische zusammensetzung mit einem extrusionszusatzstoff
Abstract: Beschrieben sind pharmazeutische Zusammensetzungen, erhaltlich durch Mischen mindestens eines Wirkstoffes mit mindestens einem Extrusionszusatzstoff aus der Gruppe der mit Fettsauren veresterten Polyalkohole und gemeinsamer Schmelzextrusion.