S
Stephan C. Hammer
Researcher at University of Stuttgart
Publications - 27
Citations - 1059
Stephan C. Hammer is an academic researcher from University of Stuttgart. The author has contributed to research in topics: Chemistry & Catalysis. The author has an hindex of 12, co-authored 18 publications receiving 826 citations. Previous affiliations of Stephan C. Hammer include Bielefeld University & California Institute of Technology.
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New Generation of Biocatalysts for Organic Synthesis
TL;DR: The advantages and applications of the most recent and attractive biocatalysts--reductases, transaminases, ammonia lyases, epoxide hydrolases, and dehalogenases--will be discussed herein and exemplified by the syntheses of interesting compounds.
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Design and Evolution of Enzymes for Non-natural Chemistry
TL;DR: This work discusses recent examples, showcases catalyst improvements achieved using directed evolution, and comment on some current and future implications of non-natural enzyme evolution for sustainable chemical synthesis.
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Anti-Markovnikov alkene oxidation by metal-oxo-mediated enzyme catalysis.
TL;DR: The engineering of a cytochrome P450 enzyme by directed evolution to catalyze metal-oxo–mediated anti-Markovnikov oxidation of styrenes with high efficiency is reported.
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Imine Reductase-Catalyzed Intermolecular Reductive Amination of Aldehydes and Ketones
TL;DR: The asymmetric imine reductase‐catalyzed intermolecular reductive amination with NADPH as the hydrogen source was investigated and constitutes a powerful and direct method for the synthesis of valuable amines under mild reaction conditions.
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Squalene hopene cyclases are protonases for stereoselective Brønsted acid catalysis
TL;DR: Active site engineering of this highly evolvable enzyme yielded a platform for enzymatic Brønsted acid catalysis in water, enabling the highly stereoselective syntheses of various cyclohexanoids while uncoupling SHC from polycyclization chemistry.