S
Stephan O. Adler
Researcher at Humboldt University of Berlin
Publications - 11
Citations - 50
Stephan O. Adler is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 3, co-authored 8 publications receiving 24 citations.
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Posted ContentDOI
Geospatially Referenced Demographic Agent-Based Modeling of SARS-CoV-2-Infection (COVID-19) Dynamics and Mitigation Effects in a Real-world Community
Björn Goldenbogen,Stephan O. Adler,Oliver Bodeit,Oliver Bodeit,Jah Wodke,Aviv Korman,Lasse Bonn,Ximena Escalera-Fanjul,Jel Haffner,Maxim Karnetzki,Maria Krantz,Ivo Maintz,Lisa Mallis,RU Moran Torres,Hannah Prawitz,Patrick Steven Segelitz,Martin Seeger,Rune Linding,Edda Klipp +18 more
TL;DR: The GERDA-1 model is the first model able to predict a bimodal behavior of SARS-Cov-2 infection dynamics and can predict infection dynamics under normal conditions and test the effect of different mitigation scenarios such as school closures, reduced social contacts as well as closure or reopening of public/work spaces.
Posted ContentDOI
Optimality in COVID-19 vaccination strategies determined by heterogeneity in human-human interaction networks
Bjoern Goldenbogen,Stephan O. Adler,Oliver Bodeit,Oliver Bodeit,Judith A. H. Wodke,Ximena Escalera-Fanjul,Aviv Korman,Maria Krantz,Lasse Bonn,Rafael Ubaldo Moran Torres,Johanna El Haffner,Maxim Karnetzki,Ivo Maintz,Lisa Mallis,Hannah Prawitz,Patrick Steven Segelitz,Martin Seeger,Rune Linding,Edda Klipp +18 more
TL;DR: This work introduces a model that predicts the effect of vaccination into an ongoing COVID-19 outbreak using precision simulation of human-human interaction and infection networks and shows that simulations incorporating non-linear network complexity and local heterogeneity can enable governance with performance-quantified vaccination strategies.
Journal ArticleDOI
Identification of small non-coding RNAs responsive to GUN1 and GUN5 related retrograde signals in Arabidopsis thaliana.
Kristin Habermann,Bhavika Tiwari,Maria Krantz,Stephan O. Adler,Edda Klipp,M. Asif Arif,Wolfgang Frank +6 more
TL;DR: Based on the comprehensive changes in sRNA expression, a considerable impact of sRNAs in retrograde-dependent transcriptional changes to adjust plastidic and nuclear gene expression is assumed.
Journal ArticleDOI
Control of COVID‐19 Outbreaks under Stochastic Community Dynamics, Bimodality, or Limited Vaccination
Björn Goldenbogen,Stephan O. Adler,Oliver Bodeit,Judith A. H. Wodke,Ximena Escalera-Fanjul,Aviv Korman,Maria Krantz,Lasse Bonn,Rafael Morán-Torres,Johanna El Haffner,Maxim Karnetzki,Ivo Maintz,Lisa Mallis,Hannah Prawitz,P. Segelitz,M Seeger,Rune Linding,Edda Klipp +17 more
TL;DR: The authors demonstrate that the threshold for population immunity is not a unique number, but depends on the vaccination strategy, and suggests prioritizing highly interactive people diminishes the risk for an infection wave, while prioritizing the elderly minimizes fatalities when vaccinations are low.
Journal ArticleDOI
Chemical Reaction Networks Possess Intrinsic, Temperature-Dependent Functionality.
Stephan O. Adler,Edda Klipp +1 more
TL;DR: It is demonstrated that even simple network motifs can exhibit temperature-dependent functional features resulting from the interplay of network structure and the distribution of activation energies over the involved reactions, expanding the scope of thermodynamic modelling of biochemical processes by addressing further possibilities and effects.