Stephanie L. Servetas

TL;DR: Overall, the benchtop platforms perform well for identification of pathogens from a representative clinical sample, but unlike identification, characterization of pathogens is likely to require higher titers, multiple libraries and/or multiple sequencing runs.

TL;DR: Recent findings concerning H. pylori biofilm structure or the genes associated with this mode of growth are highlighted and the potential roles of biofilms in the failure of antibiotic treatment and in infection recurrence are discussed.

TL;DR: Analysis of isogenic mutant strains that contained all possible single, double, and triple regulatory mutations in Fur, NikR, and ArsS revealed a previously unrecognized role for the acid-responsive two-component system ArsRS in biofilm formation.

TL;DR: The results indicate that while various types of growth media did not dramatically affect biofilm formation, surface selection had a significant effect on the final biofilm mass and novel insight is provided into optimal biofilm conditions, the biofilm matrix, and possible mechanisms to block or disruptBiofilm formation.

TL;DR: Investigation of homB expression, regulation, and contribution to biofilm formation suggests that the ArsRS-dependent regulation of OMPs such as HomB may be one mechanism by which ArsRS dictates biofilm development in a pH responsive manner.