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Stéphanie Lacotte
Researcher at University of Geneva
Publications - 44
Citations - 1658
Stéphanie Lacotte is an academic researcher from University of Geneva. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 16, co-authored 35 publications receiving 1457 citations. Previous affiliations of Stéphanie Lacotte include Centre national de la recherche scientifique & University of Trieste.
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Journal ArticleDOI
Functionalized Carbon Nanotubes Are Non-Cytotoxic and Preserve the Functionality of Primary Immune Cells
Hélène Dumortier,Stéphanie Lacotte,Giorgia Pastorin,Riccardo Marega,Wei Wu,Davide Bonifazi,Jean-Paul Briand,Maurizio Prato,Sylviane Muller,Alberto Bianco +9 more
TL;DR: It is found that f-CNT 3, which instead possesses reduced solubility and forms mainly stable water suspensions, preserved lymphocytes' functionality while provoking secretion of proinflammatory cytokines by macrophages.
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CXCR3, Inflammation, and Autoimmune Diseases
TL;DR: What the authors know today about the nature and functions of CXCR3 is reviewed, with special emphasis on its involvement in two main rheumatic systemic autoimmune diseases, namely rheumatoid arthritis and systemic lupus erythematosus.
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Intraportal islet transplantation: the impact of the liver microenvironment.
Vaihere Delaune,Vaihere Delaune,Thierry Berney,Thierry Berney,Stéphanie Lacotte,Christian Toso,Christian Toso +6 more
TL;DR: This review focuses on the specifics of the liver microenvironment, notably the localized hepatic ischemia/reperfusion injury following transplantation, the low oxygenation of the portal vein, the instant blood‐mediated inflammatory reaction, the endogenous liver immune system, and the gut–liver axis, and how they can each have an impact on the transplanted islets.
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Early Differentiated CD138highMHCII+IgG+ Plasma Cells Express CXCR3 and Localize into Inflamed Kidneys of Lupus Mice
Stéphanie Lacotte,Marion Decossas,Carole Le Coz,Susana Brun,Sylviane Muller,Hélène Dumortier +5 more
TL;DR: Early differentiatedCD138highMHCII+ rather than terminally differentiated CD138highmHCIIlow plasma cells may be involved in the renal inflammatory injury in lupus, due to CXCR3 expression and IgG secretion.
Journal ArticleDOI
Effects of the gut–liver axis on ischaemia-mediated hepatocellular carcinoma recurrence in the mouse liver
Lorenzo A. Orci,Stéphanie Lacotte,Vaihere Delaune,Florence Slits,Graziano Oldani,Vladimir Lazarevic,Carlo Rossetti,Laura Rubbia-Brandt,Laura Rubbia-Brandt,Philippe Morel,Christian Toso +10 more
TL;DR: It is suggested that intestinal venous congestion, which often occurs during liver surgery, favors the translocation of gut-derived bacterial products in the portal vein, thereby facilitating cancer recurrence by enhancing the signaling of Toll-like receptor 4 in the liver.