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Stéphanie Lacotte

Researcher at University of Geneva

Publications -  44
Citations -  1658

Stéphanie Lacotte is an academic researcher from University of Geneva. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 16, co-authored 35 publications receiving 1457 citations. Previous affiliations of Stéphanie Lacotte include Centre national de la recherche scientifique & University of Trieste.

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Functionalized Carbon Nanotubes Are Non-Cytotoxic and Preserve the Functionality of Primary Immune Cells

TL;DR: It is found that f-CNT 3, which instead possesses reduced solubility and forms mainly stable water suspensions, preserved lymphocytes' functionality while provoking secretion of proinflammatory cytokines by macrophages.
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CXCR3, Inflammation, and Autoimmune Diseases

TL;DR: What the authors know today about the nature and functions of CXCR3 is reviewed, with special emphasis on its involvement in two main rheumatic systemic autoimmune diseases, namely rheumatoid arthritis and systemic lupus erythematosus.
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Intraportal islet transplantation: the impact of the liver microenvironment.

TL;DR: This review focuses on the specifics of the liver microenvironment, notably the localized hepatic ischemia/reperfusion injury following transplantation, the low oxygenation of the portal vein, the instant blood‐mediated inflammatory reaction, the endogenous liver immune system, and the gut–liver axis, and how they can each have an impact on the transplanted islets.
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Early Differentiated CD138highMHCII+IgG+ Plasma Cells Express CXCR3 and Localize into Inflamed Kidneys of Lupus Mice

TL;DR: Early differentiatedCD138highMHCII+ rather than terminally differentiated CD138highmHCIIlow plasma cells may be involved in the renal inflammatory injury in lupus, due to CXCR3 expression and IgG secretion.
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Effects of the gut–liver axis on ischaemia-mediated hepatocellular carcinoma recurrence in the mouse liver

TL;DR: It is suggested that intestinal venous congestion, which often occurs during liver surgery, favors the translocation of gut-derived bacterial products in the portal vein, thereby facilitating cancer recurrence by enhancing the signaling of Toll-like receptor 4 in the liver.