Stephen M. Rappaport

TL;DR: A more comprehensive and quantitative view of environmental exposure is needed if epidemiologists are to discover the major causes of chronic diseases.

TL;DR: Two genetic variants in key metabolizing enzymes, myeloperoxidase and NAD(P)H:quinone oxidoreductase, influenced susceptibility to benzene hematotoxicity and may be particularly evident among genetically susceptible subpopulations.

TL;DR: Key recommendations made during the workshop included more coordination of efforts; development of new databases, software tools, and chemical libraries for the food metabolome; and shared repositories of metabolomic data.

TL;DR: A database of approximately 20,000 chemical exposures has been constructed in close co-operation between the School of Public Health of the University of North Carolina at Chapel Hill and the Department of Air Pollution of the Wageningen Agricultural University, and it was shown that environmental and production factors were shown to have distinct influences on the within-worker (day-to-day) variability, but not on the between-worker variability.

TL;DR: Environmental exposures after the WTC disaster were associated with significant adverse effects on health, and the high alkalinity of WTC dust produced bronchial hyperreactivity, persistent cough, and increased risk of asthma.