S
Su Yi Tseng
Researcher at Johns Hopkins University School of Medicine
Publications - 2
Citations - 918
Su Yi Tseng is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Cancer & Natural killer T cell. The author has an hindex of 1, co-authored 1 publications receiving 867 citations.
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B7-Dc, a New Dendritic Cell Molecule with Potent Costimulatory Properties for T Cells
Su Yi Tseng,Mizuto Otsuji,Kevin S. Gorski,Xin Huang,Jill E. Slansky,Sara I. Pai,Ahmed Shalabi,Tahiro Shin,Drew M. Pardoll,Haruo Tsuchiya +9 more
TL;DR: A new B7 family member, B7-DC, whose expression is highly restricted to DCs, was identified among a library of genes differentially expressed between DCs and activated macrophages, which may account for some of the unique activity of DC's, such as their ability to initiate potent T helper cell type 1 responses.
Journal ArticleDOI
Abstract 2866: BAY 3375968: An afucosylated anti-CCR8 antibody depleting activated intratumoral regulatory T cells as a cancer immunotherapy
Helge G. Roider,Su Yi Tseng,S. Hoff,Sandra Berndt,Katharina Filarski,Uwe Gritzan,Beatrix Stelte-Ludwig,Wiebke Nadler,Joanna Grudzinska-Goebel,P. J. Ellinger,Mark Trautwein,Mátyás Gorjánácz +11 more
TL;DR: CCR8 is a novel Treg depleting immunotherapy target, and due to its highly tumor-restricted expression profile, BAY 3375968 may provide superior clinical safety and efficacy profile comparing to other less specific Treg targeting approaches.