S
Sufang Chu
Researcher at Xuzhou Medical College
Publications - 24
Citations - 428
Sufang Chu is an academic researcher from Xuzhou Medical College. The author has contributed to research in topics: Medicine & Carcinogenesis. The author has an hindex of 5, co-authored 11 publications receiving 105 citations.
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Journal ArticleDOI
LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification
Pingfu Hou,Sen Meng,Minle Li,Tian Lin,Sufang Chu,Zhongwei Li,Junnian Zheng,Yuming Gu,Jin Bai +8 more
TL;DR: LINC00460 can serve as a promising predictive biomarker for the diagnosis and prognosis among patients with CRC through interacting with IGF2BP2 and DHX9 and bind to the m6A modified HM GA1 mRNA to enhance the HMGA1 mRNA stability.
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Functional roles of circular RNAs during epithelial-to-mesenchymal transition.
Bing-Qing Shang,Minle Li,Hao-yu Quan,Pingfu Hou,Zhongwei Li,Sufang Chu,Junnian Zheng,Jin Bai +7 more
TL;DR: This work provides a theoretical basis for the use of EMT-related circRNAs in targeted management and therapy of various cancers and discusses the wayscircRNAs can regulate EMT progression through EMT transcription factors, E MT-related signaling pathways, and other mechanisms.
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DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer.
TL;DR: DKC1 appears to regulate CRC angiogenesis and metastasis through directly activating HIF-1α transcription, and can serve as an accurate indicator in predicting the prognosis of patients with CRC and act as a potential therapeutic target for CRC.
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Post-translational modifications of EZH2 in cancer.
Zhongwei Li,Minle Li,Diandian Wang,Pingfu Hou,Xintian Chen,Sufang Chu,Dafei Chai,Junnian Zheng,Jin Bai +8 more
TL;DR: An overview of different roles of EZH2 modification and EZh2-PTMs crosstalk during tumorigenesis and cancer metastasis is presented and the therapeutic potential of targeting EzH2 modifications for cancer therapy is discussed.
Journal ArticleDOI
Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas
Yan Wang,C. Wu,Yu Du,Zhongwei Li,Minle Li,Pingfu Hou,Zhigang Shen,Sufang Chu,Junnian Zheng,Jin Bai +9 more
TL;DR: In this paper , the progress and exclusive characteristics of circRNA translation and highlights the latest mechanisms and regulation of the circRNA translatomics are discussed, and extensive functions and mechanisms of non-canonical circRNA-derived proteins in human diseases are summarized.