Suman Sinha

TL;DR: A general, efficient, and environmentally benign method for the one-pot cascade synthesis of quinazolin-4(3H)-ones via acceptorless dehydrogenative coupling of o-aminobenzamide with alcohols catalyzed by a simple Ni(II) catalyst, featuring a tetraaza macrocyclic ligand (tetramethyltetraaza[14]annulene (MeTAA).

TL;DR: Insight was carried out into the reaction mechanism which shows that the nickel and the coordinated diamine ligands participate in a synergistic way during the dehydrogenation of alcohols.

TL;DR: Two environmentally benign methods for the synthesis of quinazolines via acceptorless dehydrogenative coupling of 2-aminobenzylamine with benzyl alcohol and benzonitrile and tetraaza macrocyclic ligands are reported.

TL;DR: Control experiments and deuterium labelling studies indicate that both copper and the coordinated azo-aromatic ligand participate in a cooperative manner during the catalytic cycle.

TL;DR: A general, efficient and environmentally benign, one-step synthesis of substituted quinoline derivatives was achieved by acceptorless dehydrogenative coupling of o-aminobenzylalcohols with ketones and secondary alcohols catalyzed by a cheap, earth abundant and easy to prepare nickel catalyst.