S
Sumita Bandyopadhyay
Researcher at University of Calcutta
Publications - 21
Citations - 730
Sumita Bandyopadhyay is an academic researcher from University of Calcutta. The author has contributed to research in topics: Messenger RNA & Nucleolin. The author has an hindex of 13, co-authored 21 publications receiving 646 citations. Previous affiliations of Sumita Bandyopadhyay include Bose Institute & Medical University of South Carolina.
Papers
More filters
Journal ArticleDOI
Identification of Nucleolin as an AU-rich Element Binding Protein Involved in bcl-2 mRNA Stabilization *
TL;DR: It is suggested that nucleolin functions as a bcl-2-stabilizing factor and that taxol and okadaic acid treatment induces apoptosis in HL-60 cells through a process that involves down-regulation of nucleolin and destabilization of bCl-2 mRNA.
Journal ArticleDOI
Mechanism of Regulation of bcl-2 mRNA by Nucleolin and A+U-rich Element-binding Factor 1 (AUF1)
Daniella Ishimaru,Lisa Zuraw,Sivakumar Ramalingam,Tapas K. Sengupta,Sumita Bandyopadhyay,Adrian Reuben,Daniel J. Fernandes,Eleanor K. Spicer +7 more
TL;DR: A model is proposed that illustrates the opposing roles of nucleolin and AUF1 in regulating bcl-2 mRNA stability by examining the site on the bCl-2 3′-untranslated region that is bound by nucleolin as well as the protein binding domains important for bcl -2 mRNA recognition.
Journal ArticleDOI
Regulation of Bcl-2 expression by HuR in HL60 leukemia cells and A431 carcinoma cells.
Daniella Ishimaru,Sivakumar Ramalingam,Tapas K. Sengupta,Sumita Bandyopadhyay,Stephanie Dellis,Baby G. Tholanikunnel,Daniel J. Fernandes,Eleanor K. Spicer +7 more
TL;DR: Overexpression of the proto-oncogene bcl-2 promotes abnormal cell survival by inhibiting apoptosis and HuR seems to play a positive role in both regulation of bCl-2 mRNA translation and mRNA stability.
Journal ArticleDOI
Retinoid-induced apoptosis in HL-60 cells is associated with nucleolin down-regulation and destabilization of Bcl-2 mRNA.
TL;DR: Evidence is provided that ATRA-induced apoptosis is a consequence of cellular differentiation, which leads to nucleolin down- regulation and bcl-2 mRNA instability, which is accompanied by down-regulation of the cytoplasmic levels of nucleolin, a bcl -2 mRNA-stabilizing protein.
Journal ArticleDOI
Identification of Ebp1 as a component of cytoplasmic bcl-2 mRNP (messenger ribonucleoprotein particle) complexes.
TL;DR: Results indicate a novel function for Ebp1 in contributing to the regulation of bcl-2 expression in HL-60 cells, which was associated with decreased binding of trans-acting factors to bCl-2 mRNA.