S
Suresh M. Kumar
Researcher at University of Pennsylvania
Publications - 22
Citations - 1711
Suresh M. Kumar is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Melanoma & Gene knockdown. The author has an hindex of 17, co-authored 22 publications receiving 1618 citations. Previous affiliations of Suresh M. Kumar include Pennsylvania State University.
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Journal ArticleDOI
Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles
Hong Yu,Douglas D. Fang,Suresh M. Kumar,Ling Li,Thiennga K. Nguyen,Geza Acs,Meenhard Herlyn,Xiaowei Xu +7 more
TL;DR: The data suggest that human embryonic stem cell medium can be used to isolate and expand human adult stem cells, and these cells appear to be located in the bulge area of human hair follicles.
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Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation
Suresh M. Kumar,Shujing Liu,Hezhe Lu,Hongtao Zhang,Paul J. Zhang,Phyllis A. Gimotty,Matthew Guerra,Wei Guo,Xiaowei Xu +8 more
TL;DR: It is shown that expression of Oct4 gene or transmembrane delivery ofOct4 protein promoted dedifferentiation of melanoma cells to CSC-like cells, suggesting that CSC phenotype is dynamic and may be acquired through dedifferentiated cells.
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Metal Organic Resin Derived Barium Titanate: I, Formation of Barium Titanium Oxycarbonate Intermediate
TL;DR: In this article, it was shown that an intermediate barium titanium oxycarbonate phase forms between 500 and 620C and that BaTiO[sub 3] forms directly by the endothermic decomposition of this phase between 635 and 700C.
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MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1–Snail1 pathway in melanoma
Shujing Liu,Suresh M. Kumar,Hezhe Lu,Aihua Liu,Ruifeng Yang,Anitha Pushparajan,Wei Guo,Xiaowei Xu +7 more
TL;DR: This study finds a new mechanism that miR‐9 utilizes to decrease E‐cadherin expression and inhibit melanoma progression through down‐regulation of the NF‐κB1‐Snail1 pathway.
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Mutant V600E BRAF Increases Hypoxia Inducible Factor-1α Expression in Melanoma
Suresh M. Kumar,Hong Yu,Robin H. Edwards,Lianjun Chen,Steven Kazianis,Patricia Brafford,Geza Acs,Meenhard Herlyn,Xiaowei Xu +8 more
TL;DR: The data show for the first time that BRAF(V600E) mutation increases Hif-1alpha expression and melanoma cell survival under hypoxic conditions and suggest that effects of the oncogenic V600E BRAF mutation may be partially mediated through the HIF-1 alpha pathway.