S
Susan E. Lanzendorf
Researcher at Eastern Virginia Medical School
Publications - 47
Citations - 2076
Susan E. Lanzendorf is an academic researcher from Eastern Virginia Medical School. The author has contributed to research in topics: Sperm & Oocyte. The author has an hindex of 23, co-authored 47 publications receiving 2012 citations.
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Journal ArticleDOI
A preclinical evaluation of pronuclear formation by microinjection of human spermatozoa into human oocytes.
Susan E. Lanzendorf,Mary K. Maloney,Lucinda L. Veeck,James H. Slusser,Gary D. Hodgen,Zev Rosenwaks +5 more
TL;DR: Oocytes from 5 of 11 patients microinjected with human spermatozoa demonstrated successful pronuclear formation and correlated with the incidence of pregnancy in these patients transferred with same-source oocytes inseminated by standard protocols, promoting the supposition of clinical feasibility of assisted fertilization by sperm microinjection.
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Evaluation of the spindle apparatus of in-vitro matured human oocytes following cryopreservation
Stavroula G. Baka,Thomas L. Toth,Lucinda L. Veeck,Howard W. Jones,Suheil J. Muasher,Susan E. Lanzendorf +5 more
TL;DR: The results suggest that cryopreservation of the prophase I human oocyte does not significantly increase abnormalities in the resulting meiotic spindle.
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Intracytoplasmic sperm injection: achievement of high pregnancy rates in couples with severe male factor infertility is dependent primarily upon female and not male factors.
Sergio Oehninger,Lucinda L. Veeck,Susan E. Lanzendorf,Mary K. Maloney,James P. Toner,Suheil J. Muasher +5 more
TL;DR: Intracytoplasmic sperm injection offers a new and powerful therapeutic option to treat couples with severe male factor infertility associated with a variety of sperm abnormalities and an adequate female age is a pivotal factor determining a successful outcome.
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Fertilization and in vitro development of cryopreserved human prophase I oocytes
Thomas L. Toth,Stavroula G. Baka,Lucinda L. Veeck,Howard W. Jones,Suheil J. Muasher,Susan E. Lanzendorf +5 more
TL;DR: Prophase I oocytes from stimulated IVF cycles are able to survive cryopreservation and resume meiosis to achieve full nuclear maturation post-thaw and retain the same capacity for fertilization and development as control oocytes.
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Expression of mRNAs for DNA methyltransferases and methyl-CpG-binding proteins in the human female germ line, preimplantation embryos, and embryonic stem cells.
John Huntriss,M. Hinkins,Brian G. Oliver,Sarah E. Harris,J.C. Beazley,Anthony J. Rutherford,R.G. Gosden,Susan E. Lanzendorf,Helen M. Picton +8 more
TL;DR: Monitoring of the expression of the mRNAs of DNA methyltransferases, methyl‐CpG‐binding domain proteins, and CpG binding protein in a developmental series of amplified cDNA samples derived from staged human ovarian follicles, oocytes, preimplantation embryos, human embryonic stem (hES) cells and in similar murine c DNA samples demonstrated an association of the DNMT3b1 transcript variant with totipotent and pluripotent human cells.