Journal ArticleDOI
Fertilization and in vitro development of cryopreserved human prophase I oocytes
Thomas L. Toth,Stavroula G. Baka,Lucinda L. Veeck,Howard W. Jones,Suheil J. Muasher,Susan E. Lanzendorf +5 more
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TLDR
Prophase I oocytes from stimulated IVF cycles are able to survive cryopreservation and resume meiosis to achieve full nuclear maturation post-thaw and retain the same capacity for fertilization and development as control oocytes.About:
This article is published in Fertility and Sterility.The article was published on 1994-05-01. It has received 135 citations till now. The article focuses on the topics: In vitro maturation & Human fertilization.read more
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Journal ArticleDOI
Maturation of human oocytes in vitro and their developmental competence
TL;DR: More research is needed to describe the molecular and cellular events, the presence of checkpoints and the role of gene expression, translation and protein uptake on completing oocyte maturation in vitro and in vivo and the success rates achieved in some of these special applications are clinically valuable.
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Maturation in vitro of immature human oocytes for clinical use
Kwang-Yul Cha,Ri-Cheng Chian +1 more
TL;DR: Human oocyte maturation is considered as the reinitiation and completion of the first meiotic division from the germinal vesicle stage (prophase I) to metaphase II, and the accompanying cytoplasmic maturation for fertilization and early embryonic development.
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Cryopreservation of human ovarian tissue using dimethylsulphoxide and propanediol-sucrose as cryoprotectants
Outi Hovatta,Rene Silye,Thomas Krausz,Ronit Abir,Raul Margara,Geoffrey Trew,Amir Lass,Robert M.L. Winston +7 more
TL;DR: The results suggest that cryopreservation of human ovarian tissue is feasible, however, the normality of the oocytes taken from tissue which has been frozen still needs to be established.
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Cryopreservation of immature human oocytes and ovarian tissue: An emerging technology?☆
TL;DR: The disappointing results obtained with the cryopreservation of oocytes at metaphase II and ethical concerns about embryo storage are giving impetus to the banking of ovarian tissue for patients who require conservation of fertility.
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Birth after cryopreservation of immature oocytes with subsequent in vitro maturation
TL;DR: This case report proves the feasibility if not the efficiency of using immature oocytes for cryostorage, coupling both cryopreservation and in vitro maturation, and delivers an apparently healthy female infant at 40 weeks.
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Journal ArticleDOI
Pregnancy after human oocyte cryopreservation
TL;DR: The first successful attempt at deep freezing and thawing of the human oocyte is reported and a twin pregnancy was achieved after insemination and replacement in utero.
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Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program *
TL;DR: In this paper, the results with immature human follicular oocytes harvested from unstimulated ovaries, matured in vitro, fertilized, and transferred to an agonadal recipient were described.
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Transient cooling to room temperature can cause irreversible disruption of the meiotic spindle in the human oocyte
TL;DR: The effect of cooling to room temperature for either 10 or 30minutes on the microtubule system of oocytes has been investigated in this article, showing that the spindles in oocytes that were cooled for either one or four hours were found to resemble those in non-cooled control oocytes in less than one half of the cases examined.