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Susan M. North
Researcher at University of Texas at Austin
Publications - 12
Citations - 316
Susan M. North is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Antibody & Monoclonal antibody. The author has an hindex of 8, co-authored 12 publications receiving 313 citations. Previous affiliations of Susan M. North include University of Texas MD Anderson Cancer Center & University of Texas System.
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Journal Article
Amplified and Overexpressed Epidermal Growth Factor Receptor Gene in Uncultured Primary Human Breast Carcinoma
Jungsil Ro,Susan M. North,Gary E. Gallick,Gabriel N. Hortobagyi,Jordan U. Gutterman,Mark Blick +5 more
TL;DR: It is demonstrated by immunohistochemistry using a monoclonal antibody to the epidermal growth factor receptor that the receptor protein product of this gene was overexpressed and displayed elevated kinase activity.
Journal Article
Transforming growth factor-alpha production and autoinduction in a colorectal carcinoma cell line (DiFi) with an amplified epidermal growth factor receptor gene.
Seema Untawale,M. A. Zorbas,C P Hodgson,Robert J. Coffey,Gary E. Gallick,Susan M. North,David M. Wildrick,Matilde Olive,Mark Blick,Lynn C. Yeoman +9 more
TL;DR: DiFi colorectal cancer cells uniquely show production and auto-induction of TGF-alpha in addition to amplification and overexpression of the EGFR gene, these cells represent a valuable tool for studying the role(s) of theEGFR in the regulation of tumor cell growth.
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Effects of mast cell-macrophage interactions on the production of collagenolytic enzymes by metastatic tumor cells and tumor-derived and stromal fibroblasts.
TL;DR: Normal infiltrating host cells such as macrophage- and degranulated mast cells can have profound effects on the production of degradative enzymes by tumor cells and tumor-associated stromal fibroblasts.
Journal Article
Heterogeneity in the sensitivities of the 13762NF rat mammary adenocarcinoma cell clones to cytolysis mediated by extra- and intratumoral macrophages.
Susan M. North,Garth L. Nicolson +1 more
TL;DR: The susceptibility of cloned cell lines of the 13762NF rat mammary adenocarcinoma to macrophage-mediated cytolysis was investigated using both intra- and extratumoral macrophages and showed a function of effector as well as target cell source.
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Glycoprotein profiles of macrophages at different stages of activation as revealed by lectin binding after electrophoretic separation.
TL;DR: The PWM isolectin may serve as a marker for an early stage of MΦ activation by examining the reactivity of varous lectins to the glycoproteins separated by polyacrylamide gel electrophoresis.