S
Susanne Carlsson
Researcher at Lund University
Publications - 7
Citations - 1150
Susanne Carlsson is an academic researcher from Lund University. The author has contributed to research in topics: Galectin & Glycan. The author has an hindex of 7, co-authored 7 publications receiving 1070 citations. Previous affiliations of Susanne Carlsson include University of Waterloo.
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Journal ArticleDOI
Introduction to galectins
TL;DR: A brief introduction to the galectins as a protein family with some comments on nomenclature is given.
Journal ArticleDOI
Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface
Susanne Carlsson,Christopher T. Öberg,Michael C. Carlsson,Anders Sundin,Ulf J. Nilsson,David Smith,Richard D. Cummings,Jenny Almkvist,Anna Karlsson,Hakon Leffler +9 more
TL;DR: Galectin-8 binding and signaling at cell surfaces can be explained by combined binding of the two CRDs to low or medium affinity ligand, and their highest affinity ligands, such as sialylated galactosides, are not required.
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Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells.
Santosh Kumar Patnaik,Barry Potvin,Susanne Carlsson,David Sturm,Hakon Leffler,Pamela Stanley +5 more
TL;DR: Binding of the galectins to the different CHO glycosylation mutants revealed that complex N-glycans are the major ligands for each galectin except the N-terminal CRD of galectine-8, and also identified some fine differences in glycan recognition.
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Synthesis of a phenyl thio--D-galactopyranoside library from 1,5-difluoro-2,4-dinitrobenzene: discovery of efficient and selective monosaccharide inhibitors of galectin-7
TL;DR: The synthesis of a library of 28 compounds that showed variable inhibitory activity against the different galectins and have potential as structurally simple and selective tools for dissecting biological functions of galectin-7 are reported.
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Intracellular sorting of galectin-8 based on carbohydrate fine specificity.
TL;DR: A role of galectin fine specificity for intracellular targeting is found in Chinese hamster ovary cells and in a mutant (Lec2) lacking sialylated glycans, by fluorescence microscopy.