S
Suzanne Cory
Researcher at Walter and Eliza Hall Institute of Medical Research
Publications - 198
Citations - 43144
Suzanne Cory is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Transgene & Gene. The author has an hindex of 79, co-authored 196 publications receiving 41734 citations. Previous affiliations of Suzanne Cory include Royal Melbourne Hospital & University of Geneva.
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The Bcl-2 Protein Family: Arbiters of Cell Survival
Jerry M. Adams,Suzanne Cory +1 more
TL;DR: Bcl-2 and related cytoplasmic proteins are key regulators of apoptosis, the cell suicide program critical for development, tissue homeostasis, and protection against pathogens.
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The Bcl2 family: regulators of the cellular life-or-death switch.
Suzanne Cory,Jerry M. Adams +1 more
TL;DR: A better understanding of how the Bcl2 family controls caspase activation should result in new, more effective therapeutic approaches in tissue homeostasis and cancer.
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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells.
TL;DR: Results argue that bcl-2 provided a distinct survival signal to the cell and may contribute to neoplasia by allowing a clone to persist until other oncogenes, such as c-myc, become activated.
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The Bcl-2 apoptotic switch in cancer development and therapy
J. M. Adams,Suzanne Cory +1 more
TL;DR: Better understanding of the Bcl-2 family is clarifying its role in cancer development, revealing how conventional therapy works and stimulating the search for ‘BH3 mimetics’ as a novel class of anticancer drugs.
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The c- myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
Jerry M. Adams,A W Harris,Carl A. Pinkert,Lynn M. Corcoran,Warren S. Alexander,Suzanne Cory,Richard D. Palmiter,Ralph L. Brinster +7 more
TL;DR: Transgenic mice bearing the cellular myc oncogene coupled to the immunoglobulin μ or κ enhancer frequently develop a fatal lymphoma within a few months of birth and constitutive c-myc expression appears to be highly leukaemogenic at several stages of B-cell maturation.