S
Sylvie Samain
Researcher at University of Lyon
Publications - 1
Citations - 391
Sylvie Samain is an academic researcher from University of Lyon. The author has contributed to research in topics: XIST & Non-coding RNA. The author has an hindex of 1, co-authored 1 publications receiving 379 citations. Previous affiliations of Sylvie Samain include Centre national de la recherche scientifique & Pasteur Institute.
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The Xist RNA Gene Evolved in Eutherians by Pseudogenization of a Protein-Coding Gene
Laurent Duret,Corinne Chureau,Corinne Chureau,Corinne Chureau,Sylvie Samain,Sylvie Samain,Sylvie Samain,Jean Weissenbach,Jean Weissenbach,Jean Weissenbach,Philip Avner,Philip Avner,Philip Avner +12 more
TL;DR: It is shown that Xist evolved, at least partly, from a protein-coding gene and that the loss of protein- coding function of the proto-Xist coincides with the four flanking protein genes becoming pseudogenes, which suggests that mechanisms of dosage compensation have evolved independently in both lineages.