T
T. Durst
Researcher at Carleton University
Publications - 12
Citations - 508
T. Durst is an academic researcher from Carleton University. The author has contributed to research in topics: Piperaceae & Meliaceae. The author has an hindex of 8, co-authored 12 publications receiving 484 citations.
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Journal ArticleDOI
Antimalarial Activity of Tropical Meliaceae Extracts and Gedunin Derivatives
S. MacKinnon,T. Durst,J. T. Arnason,Cindy K. Angerhofer,John M. Pezzuto,Pablo Sanchez-Vindas,Luis Poveda,M Gbeassor +7 more
TL;DR: Extracts of 22 species of Meliaceae were examined for antimalarial activity using in vitro tests with two clones of Plasmodium falciparum, one sensitive tochloroquine (W2) and one chloroquine-resistant (D6), suggesting there is no cross-resistance to chloroquines.
Journal ArticleDOI
Insecticidal Neolignans from Piper decurrens
D. Chauret,C.-B. Bernard,John T. Arnason,T. Durst,H.G. Krishnamurty,Pablo Sanchez-Vindas,N Moreno,L S Roman,Luis Poveda +8 more
TL;DR: Three known neolignans found for the first time in a species of the Piperaceae, were isolated from Piper decurrens via insecticidal bioassay-guided fractionation, along with a small quantity of a new related compound.
Journal ArticleDOI
Traditionally-used antimalarials from the Meliaceae.
S. Omar,J. Zhang,S. MacKinnon,Danna J. Leaman,T. Durst,Bernard J. R. Philogène,J. T. Arnason,Pablo Sanchez-Vindas,Luis Poveda,Pamela A. Tamez,John M. Pezzuto +10 more
TL;DR: Gedunin has significant in vitro activity but initially showed poor in vivo activity, and the results show the potential for both antimalarial drug and phytomedicine development from traditionally used plants.
Journal ArticleDOI
Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense.
Virginie Treyvaud Amiguet,Philippe Petit,Chieu Anh Ta,Ronaldo Nuñez,Pablo Sanchez-Vindas,Luis Poveda Alvarez,Myron L. Smith,John T. Arnason,T. Durst +8 more
TL;DR: Antifungal assays with the two major compounds, 1 and 2, were carried out, and results showed a high activity of 1 against Alternaria alternata, Candida albicans azole-resistant strain D10, and Wangiella dermatitides and a combination of the dialdehyde sesquiterpenes with dillapiol showed a synergistic antifungAL effect with 1 and an additive effect with 4 and 5.
Journal ArticleDOI
Methyl 4-Hydroxy-3-(3'-methyl-2'-butenyl)benzoate, Major Insecticidal Principle from Piper guanacastensis
Rogelio Pereda-Miranda,C.-B. Bernard,T. Durst,John T. Arnason,Pablo Sanchez-Vindas,Luis Poveda,L. San Roman +6 more
TL;DR: The CHCl3-soluble extract of Piper guanacastensis (Piperaceae) was found to have noteworthy insecticidal activity to Aedes atropalpus mosquito larvae.