T
T Icho
Researcher at National Institutes of Health
Publications - 2
Citations - 262
T Icho is an academic researcher from National Institutes of Health. The author has contributed to research in topics: RNA & HSPA14. The author has an hindex of 2, co-authored 2 publications receiving 253 citations.
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The double-stranded RNA genome of yeast virus L-A encodes its own putative RNA polymerase by fusing two open reading frames.
T Icho,Reed B. Wickner +1 more
TL;DR: The coding sequence of ORF2 shows a pattern characteristic of viral RNA-dependent RNA polymerases of icosahedral (+)-strand RNA viruses, whereby the 180-kDa protein is analogous to gag-pol fusion proteins.
Journal ArticleDOI
The MAK11 protein is essential for cell growth and replication of M double-stranded RNA and is apparently a membrane-associated protein.
T Icho,Reed B. Wickner +1 more
TL;DR: AMAK11-lacZ fusion that includes the entire MAK11 protein and complements the mak11-1 mutation was constructed and revealed a fusion protein monomer of 170 kDa which agrees with the predicted molecular weight.