T
T. Romero
Researcher at Harvard University
Publications - 4
Citations - 364
T. Romero is an academic researcher from Harvard University. The author has contributed to research in topics: Single-nucleotide polymorphism & Linkage disequilibrium. The author has an hindex of 3, co-authored 4 publications receiving 342 citations.
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Journal ArticleDOI
Amniotic membrane inlay and overlay grafting for corneal epithelial defects and stromal ulcers
Erik Letko,S Stechschulte,Kenneth R. Kenyon,Nadia Sadeq,T. Romero,C. Michael Samson,Quan Dong Nguyen,Stephanie L. Harper,Jonathan D. Primack,Dimitri T. Azar,Martin Grüterich,Claes H. Dohlman,Stefanos Baltatzis,C. Stephen Foster +13 more
TL;DR: The AMT can be helpful in the treatment of PED in which all other conventional management has failed, however, the success rate in this study was not as high as that previously reported, and the results showed a high incidence of recurrences of epithelial defects.
Journal ArticleDOI
Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocks.
Edmond J. Yunis,Charles E. Larsen,Marcelo Fernandez-Vina,Zuheir L. Awdeh,T. Romero,John A. Hansen,Chester A. Alper +6 more
TL;DR: The concept of the conserved extended haplotype (CEH) is updated using HLA allele identification and TNF microsatellites to show that specific combinations of the four blocks form single genetic units with a total haplotype frequency in the Caucasian population of 0.30.
Journal ArticleDOI
Genetic Fixity in the Human Major Histocompatibility Complex and Block Size Diversity in the Class I Region Including HLA-E
Viviana Romero,Charles E. Larsen,Charles E. Larsen,Jonathan S. Duke-Cohan,Edward A. Fox,T. Romero,Olga P. Clavijo,Dolores A. Fici,Zaheed Husain,Zaheed Husain,Ingrid Almeciga,Dennis R. Alford,Zuheir L. Awdeh,Joaquín Zúñiga,Lama El-Dahdah,Chester A. Alper,Chester A. Alper,Edmond J. Yunis +17 more
TL;DR: It is concluded that to generate high-resolution maps for relating MHC haplotypes to disease susceptibility, both SNP and MHC allele analysis must be conducted as complementary techniques.
Journal ArticleDOI
Linkage disequilibrium of HLA-A11 and A1 with one of the polymorphisms of the gamma-aminobutyric acid receptor type B
TL;DR: It is reported that the allele C of this SNP in the GABA(B) R1 gene is in linkage disequilibrium with HLA-A11 (P<0.00001) and to a lesser extent with Hla-A1 (P <0.01).