T
Tadeusz J. Wiktor
Researcher at Wistar Institute
Publications - 60
Citations - 4257
Tadeusz J. Wiktor is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies virus & Virus. The author has an hindex of 34, co-authored 60 publications receiving 4191 citations. Previous affiliations of Tadeusz J. Wiktor include Children's Hospital of Philadelphia & Haffkine Institute.
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Journal ArticleDOI
Characterization of an antigenic determinant of the glycoprotein that correlates with pathogenicity of rabies virus
Bernhard Dietzschold,William H. Wunner,Tadeusz J. Wiktor,A D Lopes,M. Lafon,C L Smith,Hilary Koprowski +6 more
TL;DR: It is concluded that arginine-333 is essential for the integrity of an antigenic determinant and for the ability of rabies viruses to produce lethal infection in adult mice.
Journal ArticleDOI
Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene
Tadeusz J. Wiktor,R I Macfarlan,K J Reagan,Bernhard Dietzschold,P J Curtis,William H. Wunner,Marie-Paule Kieny,Richard Lathe,J P Lecocq,M Mackett +9 more
TL;DR: V-RGpro8 virus was highly effective in priming mice to generate a secondary rabies virus-specific cytotoxic T-lymphocyte response following culture of lymphocytes with either ERA or PM strains of rabiesirus.
Journal Article
Antigenic Properties of Rabies Virus Components
TL;DR: The envelope glycoprotein of rabies virus was shown to be the antigen responsible for the induction of virus neutralizing (VN) antibody formation and for the protection of animals against subsequent challenge with rabies, which could be explained by the amount of residual glycop protein present in these preparations.
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Oral immunization and protection of raccoons (Procyon lotor) with a vaccinia-rabies glycoprotein recombinant virus vaccine.
Charles E. Rupprecht,Tadeusz J. Wiktor,David H. Johnston,Amir N. Hamir,Bernhard Dietzschold,William H. Wunner,Lawrence T. Glickman,Hilary Koprowski +7 more
TL;DR: This work demonstrates the feasibility of a recombinant virus vaccine containing the rabies glycoprotein gene for immunization of raccoons, and possibly other wildlife, to obtain long-term protection against rabies.
Journal ArticleDOI
Antigenic sites on the CVS rabies virus glycoprotein: analysis with monoclonal antibodies.
TL;DR: Antigenic variation in the glycoprotein of rabies (CVS-11) virus was studied and competition radioimmunoassay suggested that one of these three antigenic sites was topologically distinct, with the other two in close proximity.