T
Takashi Aoki
Researcher at National Cheng Kung University
Publications - 12
Citations - 395
Takashi Aoki is an academic researcher from National Cheng Kung University. The author has contributed to research in topics: Interferon & Oryzias. The author has an hindex of 7, co-authored 12 publications receiving 287 citations. Previous affiliations of Takashi Aoki include National Pingtung University of Science and Technology.
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Journal ArticleDOI
Pathogenesis of acute hepatopancreatic necrosis disease (AHPND) in shrimp.
Hung-Chiao Lai,Tze Hann Ng,Masahiro Ando,Chung-Te Lee,I-Tung Chen,Jie-Cheng Chuang,Rapeepat Mavichak,Sheng Hsiung Chang,Mi-De Yeh,Chiang Yi-An,Haruko Takeyama,Hiro-o Hamaguchi,Chu Fang Lo,Takashi Aoki,Han Ching Wang +14 more
TL;DR: It is determined that AHPND-causing strains of V. parahaemolyticus secrete the plasmid-encoded binary toxin PirAB(vp) into the culture medium, and by using minimum inhibitory concentrations, it is found that both virulent and non-virulent V.Parahaemoleticus strains were resistant to several antibiotics, suggesting that the use of antibiotics in shrimp culture should be more strictly regulated.
Journal ArticleDOI
To complete its replication cycle, a shrimp virus changes the population of long chain fatty acids during infection via the PI3K-Akt-mTOR-HIF1α pathway.
Yun Chieh Hsieh,Yi Min Chen,Chun Yuan Li,Yu Han Chang,Suh Yuen Liang,Shu-Yu Lin,Chang Yi Lin,Sheng Hsiung Chang,Yi Jan Wang,Kay-Hooi Khoo,Kay-Hooi Khoo,Takashi Aoki,Han Ching Wang +12 more
TL;DR: White spot syndrome virus (WSSV) appears to use the PI3K-Akt-mTOR pathway to induce lipid biosynthesis at 24 hpi in order to support viral morphogenesis.
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Transcriptome analysis of immune response against Vibrio harveyi infection in orange-spotted grouper (Epinephelus coioides).
Shun Maekawa,Omkar Byadgi,Yao-Chung Chen,Takashi Aoki,Haruko Takeyama,Terutoyo Yoshida,Jun-ichi Hikima,Masahiro Sakai,Pei Chi Wang,Shih-Chu Chen +9 more
TL;DR: The increase of RANKL, IL‐l&bgr;, INF‐&ggr; genes and these target genes expression indicated the activation of immune response against Vibrio harveyi infection, and transcriptome analysis of head kidney and spleen in orange‐spotted grouper at 1 and 2 days post‐infection was performed.
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TALENs-mediated gene disruption of myostatin produces a larger phenotype of medaka with an apparently compromised immune system.
Yi An Chiang,Masato Kinoshita,Shun Maekawa,Amod Kulkarni,Chu Fang Lo,Yasutoshi Yoshiura,Han Ching Wang,Takashi Aoki +7 more
TL;DR: Although the MSTN(-/-) medaka had a larger phenotype, their immune system appeared to be at least partially suppressed or undeveloped.
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Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin-mutated F4 medaka (Oryzias latipes).
Ying Chun Yeh,Masato Kinoshita,Tze Hann Ng,Yu Hsuan Chang,Shun Maekawa,Yi An Chiang,Takashi Aoki,Han Ching Wang +7 more
TL;DR: Body length and weight of the MSTN−/− F4 medaka were significantly higher than in the wild type fish, and muscle fiber density in the inner and outer compartments of the epaxial muscles was decreased, suggesting that M STN null mutation induces muscle hypertrophy.