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Chung-Te Lee

Researcher at National Cheng Kung University

Publications -  16
Citations -  1454

Chung-Te Lee is an academic researcher from National Cheng Kung University. The author has contributed to research in topics: Vibrio vulnificus & Virulence. The author has an hindex of 13, co-authored 16 publications receiving 1201 citations.

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The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin

TL;DR: It is shown that an AHPND-causing strain of V. parahaemolyticus contains a 70-kbp plasmid with a postsegregational killing system, and that the ability to cause disease is abolished by the natural absence or experimental deletion of the plasmids-encoded homologs of the Photorhabdus insect-related toxins PirA and PirB.
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Comparative Genome Analysis of Vibrio vulnificus, a Marine Pathogen

TL;DR: The genome of biotype 1 strain V. vulnificus YJ016, an etiologic agent of human mortality from seafood-borne infections, was sequenced and a super-integron (SI) was identified, and the SI region spans 139 kbp and contains 188 gene cassettes.
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Pathogenesis of acute hepatopancreatic necrosis disease (AHPND) in shrimp.

TL;DR: It is determined that AHPND-causing strains of V. parahaemolyticus secrete the plasmid-encoded binary toxin PirAB(vp) into the culture medium, and by using minimum inhibitory concentrations, it is found that both virulent and non-virulent V.Parahaemoleticus strains were resistant to several antibiotics, suggesting that the use of antibiotics in shrimp culture should be more strictly regulated.
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Draft Genome Sequences of Four Strains of Vibrio parahaemolyticus, Three of Which Cause Early Mortality Syndrome/Acute Hepatopancreatic Necrosis Disease in Shrimp in China and Thailand.

TL;DR: In this article, the authors sequenced four Vibrio parahaemolyticus strains, three of which caused serious acute hepatopancreatic necrosis disease and revealed genes related to cholera toxin and the type IV pilus/type IV secretion system, and a unique, previously unreported, large extrachromosomal plasmid that encodes a homolog to the insecticidal Photorhabdus insect-related binary toxin PirAB.
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A Common Virulence Plasmid in Biotype 2 Vibrio vulnificus and Its Dissemination Aided by a Conjugal Plasmid

TL;DR: A gene in pR99, which encoded a novel protein and had an equivalent in pC4602-2, was further shown to be essential, but not sufficient, for the resistance to eel serum and virulence for eels.