Takashi Fujisawa

TL;DR: It is demonstrated that the administration of excessive doses of arginine induces a new, noninvasive experimental model of acute necrotizing pancreatitis, and pancreatic architecture appeared almost normal after 14 days.

TL;DR: Results suggest the usefulness of G. sylvestre in the treatment of certain classes of non-insulin-dependent diabetes mellitus and show a tendency to reduce the serum glucose concentrations in the fed state and to improve the glucose tolerance.

TL;DR: It is suggested that oral administration of camostate reduces the severity of cerulein-induced acute pancreatitis by releasing endogenous secretin and by its antiprotease activity.

TL;DR: Pancreatic endocrine function in liver cirrhosis was examined in rats both in vivo and in vitro, finding that A and B cells in the cirrhotic rats had normal sensitivity to both glucose and cholecystokinin-octapeptide.

TL;DR: It is suggested that fasting lessens the severity of cerulein-induced acute pancreatitis by reducing endogenous CCK release and alleviated histological signs of pancreatitis to some extent.