T
Takeki Hirano
Researcher at Boston Children's Hospital
Publications - 35
Citations - 682
Takeki Hirano is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Short stature & Growth hormone deficiency. The author has an hindex of 15, co-authored 35 publications receiving 655 citations.
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Journal ArticleDOI
Skeletal features and growth patterns in 14 patients with haploinsufficiency of SHOX: Implications for the development of Turner syndrome
Tomoki Kosho,Koji Muroya,Toshiro Nagai,Masatoshi Fujimoto,Susumu Yokoya,Hiromi Sakamoto,Takeki Hirano,Hiroshi Terasaki,Hirofumi Ohashi,Gen Nishimura,Seiji Sato,Nobutake Matsuo,Tsutomu Ogata +12 more
TL;DR: It is suggested that haploinsufficiency of SHOX causes not only short stature but also Turner skeletal anomalies (such as short 4th metacarpals, cubitus valgus, and LWD) and that growth pattern is primarily dependent on the presence or absence of LWD.
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Recent Status in the Occurrence of Leukemia in Growth Hormone-Treated Patients in Japan
Yoshikazu Nishi,Toshiaki Tanaka,Kazue Takano,Kenji Fujieda,Yutaka Igarashi,Kunihiko Hanew,Takeki Hirano,Susumu Yokoya,Katsuhiko Tachibana,Tomohiro Saito,Shaw Watanabe +10 more
TL;DR: It is concluded that the incidence of leukemia in GH-treated patients without risk factors is not greater than that in the general population aged 0-15 yr, and a possible increased occurrence of leukemia with GH treatment appears to be limited to patients with risk factors.
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Serum concentrations of insulin, insulin-like growth factor(IGF)-I, IGF binding protein (IGFBP)-1 and -3 and growth hormone binding protein in obese children: fasting IGFBP-1 is suppressed in normoinsulinaemic obese children.
TL;DR: Interrelationships among serum levels of insulin, IFG‐I, IGF binding protein (IGFBP)‐1 and ‐3 and growth hormone bindingprotein (GHBP) in prepubertal obese children are evaluated.
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Serum leptin and insulin concentrations in prepubertal lean, obese and insulin-dependent diabetes mellitus children
TL;DR: To evaluate the relationship between serum levels of leptin and insulin in prepubertal lean, obese and insulin‐dependent diabetes mellitus (IDDM) children, a large number of children were diagnosed with either type of diabetes or both.
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Serum dipeptidyl peptidase 4 activity in children with type 1 diabetes mellitus.
Atsushi Iwabuchi,Tomohiro Kamoda,Makoto Saito,Hiroki Nozue,Isho Izumi,Takeki Hirano,Ryo Sumazaki +6 more
TL;DR: In this paper, the authors measured serum DPP4 activity and assessed its relationship to metabolic variables in T1DM children using a fluorometric assay in 43 Type 1 diabetes mellitus (T1DM) and 26 control children.