T
Takeshi Kobayashi
Researcher at Osaka University
Publications - 177
Citations - 3343
Takeshi Kobayashi is an academic researcher from Osaka University. The author has contributed to research in topics: Medicine & Virus. The author has an hindex of 31, co-authored 146 publications receiving 2771 citations. Previous affiliations of Takeshi Kobayashi include Kyoto University & Vanderbilt University.
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Journal ArticleDOI
A Plasmid-Based Reverse Genetics System for Animal Double-Stranded RNA Viruses
Takeshi Kobayashi,Annukka A.R. Antar,Karl W. Boehme,Pranav Danthi,Elizabeth A. Eby,Kristen M. Guglielmi,Geoffrey H. Holm,Elizabeth M. Johnson,Melissa S. Maginnis,Sam Naik,Wesley B. Skelton,J. Denise Wetzel,Gregory J. Wilson,James D. Chappell,Terence S. Dermody +14 more
TL;DR: In this article, a plasmid-based reverse genetics approach was used for studies of double-stranded (ds) RNA virus replication and pathogenesis and used to develop reovirus as a vaccine vector.
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An Improved Reverse Genetics System for Mammalian Orthoreoviruses
TL;DR: Improvements to the reov virus reverse genetics system enhance its applicability for studies of reovirus biology and clinical use and reduces the number of required plasmids from 10 to 4.
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Entirely plasmid-based reverse genetics system for rotaviruses
Yuta Kanai,Satoshi Komoto,Takahiro Kawagishi,Ryotaro Nouda,Naoko Nagasawa,Misa Onishi,Yoshiharu Matsuura,Koki Taniguchi,Takeshi Kobayashi +8 more
TL;DR: A plasmid-based reverse genetics system that is free from helper viruses and independent of any selection for RV is developed, which will accelerate studies of RV pathobiology, allow rational design of RV vaccines, and yield RVs suitable for screening small molecules as potential antivirals.
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Crystal structure of reovirus attachment protein σ1 in complex with sialylated oligosaccharides.
Dirk M. Reiter,Johnna M. Frierson,Elizabeth E. Halvorson,Takeshi Kobayashi,Terence S. Dermody,Thilo Stehle,Thilo Stehle +6 more
TL;DR: Insight is provided into mechanisms of reovirus attachment to cell-surface glycans and carbohydrate binding by viruses and residues 198, 202, 203, 204, and 205 are required for functional binding to sialic acid by reov virus.
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Molecular and cellular biology of Borna disease virus infection.
TL;DR: Research into Borna disease virus research will provide new insights not only into the biology of neurotropic RNA virus but also into neuropsychiatry.