Synthesis of Polyquinane Natural Products: An Update.

Highly Stereocontrolled One-Step Synthesis of anti-β-Amino Alcohols from Organoboronic Acids, Amines, and α-Hydroxy Aldehydes

Addition of carbon-centered radicals to imines and related compounds

Highly Enantioselective [3+2] Annulation of Cyclic Enol Silyl Ethers with Donor–Acceptor Cyclopropanes: Accessing 3a‐Hydroxy [n.3.0]Carbobicycles

Organic electrosynthesis is an enabling and sustainable technology, which constitutes a rapidly expanding field of research. Electrochemical approaches serve as convenient and green alternatives to ...

Organic Electrosynthesis: Applications in Complex Molecule Synthesis

Electroreduction of γ- and δ-cyano ketones in i-PrOH with Sn cathode gave α-hydroxy ketones and their dehydroxylated ketones as the intramolecularly coupled products. Guaiazulene, (-)-valeranone, polyquinanes, dihydrojasmone, methyl dihydrojasmonate, and rosaprostol have been synthesized by utilizing this electroreductive intramolecular coupling of γ- and δ-cyano ketones in one of the key steps. Similarly, electroreduction of a mixture of ketone and nitrile gave the corresponding intermolecularly coupled product

Electroorganic chemistry. 140. Electroreductively promoted intra- and intermolecular couplings of ketones with nitriles.

The intermolecular coupling of a variety of ketones with some types of O-methyl oximes took place when a mixture of both components was electrochemically reduced in i-PrOH with an Sn cathode. The product, β-methoxyamino alcohol was easily converted to β-amino alcohol by simple reduction. A chiral ligand effective for the enantioselective addition of diethylzinc to an aldehyde was easily obtained from the product formed by the electroreductive coupling of (-)-menthone with O-methylacetaldoxime. The intermolecular coupling of a ketone with a N,N-dimethylhydrazone or nitrone was also promoted by the electroreduction. Furthermore, the electroreductive coupling of a carbonyl group with an intramolecular O-methyl oxime moiety gave the corresponding cyclized product stereoselectivity

Electroorganic Chemistry. 144. Electroreductive Coupling of Ketones with O-Methyl Oximes, N,N-Dimethylhydrazones, and Nitrones. A Convenient Route to Synthesis of .beta.-Amino Alcohol

Electroreductive intermolecular coupling of ketones with O-methyl oximes. A convenient route to synthesis of 2-amino alcohols

Electroorganic Chemistry. Part 131. Electroreductive Intermolecular Coupling of Ketones with O-Methyl Oximes. A Convenient Route to Synthesis of 2-Amino Alcohols.

Electroorganic Chemistry. Part 144. Electroreductive Coupling of Ketones with O‐Methyl Oximes, N,N‐Dimethylhydrazones, and Nitrones. A Convenient Route to Synthesis of β‐Amino Alcohol.

Taku Fujimoto

Papers

Electroorganic chemistry. 140. Electroreductively promoted intra- and intermolecular couplings of ketones with nitriles.

Electroorganic Chemistry. 144. Electroreductive Coupling of Ketones with O-Methyl Oximes, N,N-Dimethylhydrazones, and Nitrones. A Convenient Route to Synthesis of .beta.-Amino Alcohol

Electroreductive intermolecular coupling of ketones with O-methyl oximes. A convenient route to synthesis of 2-amino alcohols

Electroorganic Chemistry. Part 131. Electroreductive Intermolecular Coupling of Ketones with O-Methyl Oximes. A Convenient Route to Synthesis of 2-Amino Alcohols.

Electroorganic Chemistry. Part 144. Electroreductive Coupling of Ketones with O‐Methyl Oximes, N,N‐Dimethylhydrazones, and Nitrones. A Convenient Route to Synthesis of β‐Amino Alcohol.