T
Takuo Hirose
Researcher at Tohoku Pharmaceutical University
Publications - 127
Citations - 2614
Takuo Hirose is an academic researcher from Tohoku Pharmaceutical University. The author has contributed to research in topics: Blood pressure & Population. The author has an hindex of 30, co-authored 100 publications receiving 2257 citations. Previous affiliations of Takuo Hirose include Japan Society for the Promotion of Science & Necker-Enfants Malades Hospital.
Papers
More filters
Journal ArticleDOI
Prediction of Stroke by Home “Morning” Versus “Evening” Blood Pressure Values: The Ohasama Study
Kei Asayama,Takayoshi Ohkubo,Masahiro Kikuya,Taku Obara,Hirohito Metoki,Ryusuke Inoue,Azusa Hara,Takuo Hirose,Haruhisa Hoshi,Junichiro Hashimoto,Kazuhito Totsune,Hiroshi Satoh,Yutaka Imai +12 more
TL;DR: Morning BP and evening BP provide equally useful information for stroke risk, whereas morning HT, which indicates HT specifically observed in the morning, might be a good predictor of stroke, particularly among individuals using anti-HT medication.
Journal ArticleDOI
Home Blood Pressure Variability as Cardiovascular Risk Factor in the Population of Ohasama
Kei Asayama,Masahiro Kikuya,Rudolph Schutte,Rudolph Schutte,Lutgarde Thijs,Miki Hosaka,Michihiro Satoh,Azusa Hara,Taku Obara,Ryusuke Inoue,Hirohito Metoki,Takuo Hirose,Takayoshi Ohkubo,Takayoshi Ohkubo,Jan A. Staessen,Jan A. Staessen,Yutaka Imai +16 more
TL;DR: In a general population, new indices of blood pressure variability derived from the self-measured home blood pressure did not incrementally predict outcome over and beyond mean SBP.
Journal ArticleDOI
Prognostic significance of night-time, early morning, and daytime blood pressures on the risk of cerebrovascular and cardiovascular mortality: the Ohasama Study.
Hirohito Metoki,Takayoshi Ohkubo,Masahiro Kikuya,Kei Asayama,Taku Obara,Azusa Hara,Takuo Hirose,Junichiro Hashimoto,Kazuhito Totsune,Haruhisa Hoshi,Hiroshi Satoh,Yutaka Imai +11 more
TL;DR: High BP at different times of day were associated with different subtypes of cerebrovascular and cardiovascular mortality risk, significantly associated with elevated 2 h-SBP recorded during the night and early morning periods.
Journal ArticleDOI
Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study.
Takuo Hirose,Masahiro Hashimoto,Kazuhito Totsune,Hirohito Metoki,Kei Asayama,Masahiro Kikuya,Ken Sugimoto,Tomohiro Katsuya,Takayoshi Ohkubo,Junichiro Hashimoto,Hiromi Rakugi,Kazuhiro Takahashi,Yutaka Imai +12 more
TL;DR: It is demonstrated for the first time that polymorphism of the (P)RR gene IVS5+169C>T is associated with ABP in Japanese men, which suggests that ( P)RR has a role in blood pressure regulation.
Journal ArticleDOI
Ambulatory Versus Home Versus Clinic Blood Pressure: The Association With Subclinical Cerebrovascular Diseases: The Ohasama Study
Azusa Hara,Kazushi Tanaka,Takayoshi Ohkubo,Takayoshi Ohkubo,Takeo Kondo,Masahiro Kikuya,Hirohito Metoki,Takanao Hashimoto,Michihiro Satoh,Ryusuke Inoue,Kei Asayama,Taku Obara,Takuo Hirose,Shin-ichi Izumi,Hiroshi Satoh,Yutaka Imai +15 more
TL;DR: Although the clinical indications for ambulatory blood pressure monitoring and home blood pressure measurements may overlap, the clinical significance of each method for predicting target organ damage may differ for different target organs.