T
Tamás Rőszer
Researcher at Centro Nacional de Investigaciones Cardiovasculares
Publications - 19
Citations - 2166
Tamás Rőszer is an academic researcher from Centro Nacional de Investigaciones Cardiovasculares. The author has contributed to research in topics: Inflammation & Retinoid X receptor. The author has an hindex of 14, co-authored 19 publications receiving 1665 citations. Previous affiliations of Tamás Rőszer include University of Ulm & Hungarian Academy of Sciences.
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Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms
TL;DR: Whether these M2 markers can be reliably used to identify M2 macrophages and define their functional subdivisions is discussed and an update on the novel signals of the tissue environment and the neuroendocrine system which shape the M2 activation is provided.
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The invertebrate midintestinal gland ("hepatopancreas") is an evolutionary forerunner in the integration of immunity and metabolism.
TL;DR: It is shown that mollusks and crustaceans integrate immune functions to a metabolic organ, the midintestinal gland (“hepatopancreas”), and that immunity was the primary function of the mid gastrointestinal gland cells and that their role in the intermediate metabolism has evolved during the course of their further specialization.
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Autoimmune Kidney Disease and Impaired Engulfment of Apoptotic Cells in Mice with Macrophage Peroxisome Proliferator-Activated Receptor γ or Retinoid X Receptor α Deficiency
Tamás Rőszer,María P. Menéndez-Gutiérrez,Martina I. Lefterova,Daniel Alameda,Vanessa Núñez,Mitchell A. Lazar,Thierry Fischer,Mercedes Ricote +7 more
TL;DR: It is demonstrated that stimulation of PPARγ and RXRα in macrophages facilitates apoptotic cell engulfment, and they provide a potential strategy to avoid autoimmunity against dying cells and to attenuate SLE.
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Retinoid X receptors in macrophage biology
TL;DR: The potential of RXR-controlled transcriptional programs as targets for the treatment of pathologies associated with altered macrophage function, such as atherosclerosis, insulin resistance, autoimmunity, and neurodegeneration are highlighted.
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Inflammatory Mediators and Insulin Resistance in Obesity: Role of Nuclear Receptor Signaling in Macrophages
TL;DR: The role of PPAR and LXR signaling in macrophages and current knowledge about the impact of these actions in the manifestation of IR and obesity comorbidities such as liver steatosis and diabetic osteopenia are summarized.