T
Tao Shi
Researcher at University of California, Los Angeles
Publications - 15
Citations - 3469
Tao Shi is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Cancer & Tissue microarray. The author has an hindex of 12, co-authored 13 publications receiving 3235 citations.
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Journal ArticleDOI
Global histone modification patterns predict risk of prostate cancer recurrence
David Seligson,Steve Horvath,Tao Shi,Hong Yu,Sheila Tze,Michael Grunstein,Siavash K. Kurdistani +6 more
TL;DR: Widespread changes in specific histone modifications indicate previously undescribed molecular heterogeneity in prostate cancer and might underlie the broad range of clinical behaviour in cancer patients.
Journal ArticleDOI
Unsupervised Learning With Random Forest Predictors
Tao Shi,Steve Horvath +1 more
TL;DR: The RF dissimilarity is useful for detecting tumor sample clusters on the basis of tumor marker expressions and can be described with simple thresholding rules in this application.
Journal ArticleDOI
Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation
TL;DR: This work has detected over 50 candidate genes for differential sex expression, and confirmed at least seven murine genes which show differential expression between the developing brains of male and female mice at stage 10.5 days post coitum (dpc), before any gonadal hormone influence.
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Gene expression profiling identifies molecular subtypes of gliomas.
Ruty Mehrian Shai,Tao Shi,Thomas J. Kremen,Steve Horvath,Linda M. Liau,Timothy F. Cloughesy,Paul S. Mischel,Stanley F. Nelson +7 more
TL;DR: The global transcriptional profiles of gliomas of different types and grades are distinct from each other and from the normal brain, indicating that a relatively small number of genes can be used to distinguish between these molecular subtypes.
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Identification of molecular subtypes of glioblastoma by gene expression profiling
Paul S. Mischel,Ruty Mehrian Shai,Tao Shi,Steve Horvath,Kan V. Lu,Gheeyoung Choe,David Seligson,Thomas J. Kremen,Aarno Palotie,Linda M. Liau,Timothy F. Cloughesy,Stanley F. Nelson +11 more
TL;DR: Two additional novel molecular subtypes of GBMs are uncovered, one of which is characterized by coordinate upregulation of contiguous genes on chromosome 12q13–15 and expression of both astrocytic and oligodendroglial genes that may be important in disease stratification, and in the discovery and assessment of GBM treatment strategies.