Terri B. Hyde

TL;DR: Despite high seroprevalences in some populations, a substantial percentage of women of reproductive age are CMV seronegative and thus at risk of primary CMV infection during pregnancy, and future vaccine or educational campaigns to prevent primary infection in pregnant women may need to be tailored to suit the needs of different populations.

TL;DR: In the setting of increasing macrolide use, pneumococcal resistance has become common and most resistant strains have MICs in the range in which treatment failures have been reported.

TL;DR: In this article, the authors reviewed studies of CMV shedding in bodily fluids (defined as CMV detected by culture or CMV DNA detected by polymerase chain reaction) and found that children with congenital cytomegalovirus (CMV) infection exhibited the highest prevalences of shedding, with a steep decline by age five, indicating that young children are the key transmission risk for pregnant women.

TL;DR: The relatively low rate of CMV seroconversion in most populations is encouraging for behavioural interventions and for vaccine strategies attempting to prevent infection during pregnancy.

TL;DR: Trends in the incidence of early-onset sepsis caused by organisms other than group B streptococcus in the era of antimicrobial prophylaxis are reassuring, but careful evaluation of the increase in resistant infections in very young infants is critical in the future.