Tessa N. van den Kommer

TL;DR: The death of a child or grandchild, which may be considered a highly stressful event, was associated to a higher rate of cognitive decline, whereas more chronic stressors, such as the illness of a partner or relative, or serious conflicts, were associated with better cognitive function.

TL;DR: Depressive symptoms in older patients flag an increased likelihood of cognitive decline, and older persons with more limitations in information processing speed specifically are more vulnerable to increases in depression.

TL;DR: An independent association between high HDL cholesterol and better memory performance was found and a significant modifying effect of inflammation (C-reactive protein, α-antichymotrypsin) was found, which may be used as markers of prolonged lower cognitive functioning.

TL;DR: A nonlinear negative association between the ratio of lanosterol to cholesterol, a marker for cholesterol synthesis, and general cognition was found, and future research should focus on the interaction between (disturbed) cholesterol homeostasis and ApoE e4 status with respect to dementia.

TL;DR: Higher age, lower education, diabetes mellitus, smoking, lower body-mass index, and lower level of physical activity were associated with higher incidence of PCD, and an increase in PCD incidence over time was found.