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Tetsuya Tagami

Researcher at Kyoto Medical Center

Publications -  87
Citations -  4114

Tetsuya Tagami is an academic researcher from Kyoto Medical Center. The author has contributed to research in topics: Thyroid hormone receptor & Thyroid function. The author has an hindex of 22, co-authored 79 publications receiving 3732 citations.

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Thyroid hormone action is disrupted by bisphenol A as an antagonist.

TL;DR: The results suggest that BPA could displace T(3) from the TR and recruit a transcriptional repressor, resulting in gene suppression, the first report that B PA can antagonize T( 3) action at the transcriptional level.
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Antiatherogenic effect of pioglitazone in type 2 diabetic patients irrespective of the responsiveness to its antidiabetic effect.

TL;DR: This study represents the first demonstration of the antiatherogenic effect of pioglitazone in both nonresponders and responders with respect to its antidiabetic effect and suggests that piog litazone can exert its antiatherogensic effect independently of its antidisabetic effect.
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Leptin-to-adiponectin ratio as a potential atherogenic index in obese type 2 diabetic patients.

TL;DR: This work has demonstrated that vascular remodeling and neointimal formation are markedly attenuated in leptin-deficient ob/ob mice and db/db mice with leptin receptor mutation, suggesting that leptin may accelerate the development of vascular injury.
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Molecular Mechanism of the Inhibitory Effect of Aldosterone on Endothelial NO Synthase Activity

TL;DR: The results suggest that Aldo inhibits eNOS function through bimodal mechanisms of 5,6,7,8-tetrahydrobiopterin deficiency and protein phosphatase 2A activation and p47phox knockdown.