T
Tetsuya Tagami
Researcher at Kyoto Medical Center
Publications - 87
Citations - 4114
Tetsuya Tagami is an academic researcher from Kyoto Medical Center. The author has contributed to research in topics: Thyroid hormone receptor & Thyroid function. The author has an hindex of 22, co-authored 79 publications receiving 3732 citations.
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Journal ArticleDOI
Stomach Is a Major Source of Circulating Ghrelin, and Feeding State Determines Plasma Ghrelin-Like Immunoreactivity Levels in Humans
Hiroyuki Ariyasu,Kazuhiko Takaya,Tetsuya Tagami,Yoshihiro Ogawa,Kiminori Hosoda,Takashi Akamizu,Michio Suda,Toshikiyo Koh,Koshi Natsui,Shigetake Toyooka,Gotaro Shirakami,Takeshi Usui,Akira Shimatsu,Kentaro Doi,Hiroshi Hosoda,Masayasu Kojima,Kenji Kangawa,Kazuwa Nakao +17 more
TL;DR: It is concluded that the stomach is a major source of circulating ghrelin and that plasma gh Relin-like immunoreactivity levels reflect acute and chronic feeding states in humans.
Journal ArticleDOI
Thyroid hormone action is disrupted by bisphenol A as an antagonist.
Kenji Moriyama,Tetsuya Tagami,Takashi Akamizu,Takeshi Usui,Misa Saijo,Naotetsu Kanamoto,Yuji Hataya,Akira Shimatsu,Hideshi Kuzuya,Kazuwa Nakao +9 more
TL;DR: The results suggest that BPA could displace T(3) from the TR and recruit a transcriptional repressor, resulting in gene suppression, the first report that B PA can antagonize T( 3) action at the transcriptional level.
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Antiatherogenic effect of pioglitazone in type 2 diabetic patients irrespective of the responsiveness to its antidiabetic effect.
Noriko Satoh,Yoshihiro Ogawa,Yoshihiro Ogawa,Takeshi Usui,Tetsuya Tagami,Shigeo Kono,Hiroko Uesugi,Hiroyuki Sugiyama,Akira Sugawara,Kazunori Yamada,Akira Shimatsu,Hideshi Kuzuya,Kazuwa Nakao +12 more
TL;DR: This study represents the first demonstration of the antiatherogenic effect of pioglitazone in both nonresponders and responders with respect to its antidiabetic effect and suggests that piog litazone can exert its antiatherogensic effect independently of its antidisabetic effect.
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Leptin-to-adiponectin ratio as a potential atherogenic index in obese type 2 diabetic patients.
Noriko Satoh,Mitsuhide Naruse,Takeshi Usui,Tetsuya Tagami,Takayoshi Suganami,Kazunori Yamada,Hideshi Kuzuya,Akira Shimatsu,Yoshihiro Ogawa +8 more
TL;DR: This work has demonstrated that vascular remodeling and neointimal formation are markedly attenuated in leptin-deficient ob/ob mice and db/db mice with leptin receptor mutation, suggesting that leptin may accelerate the development of vascular injury.
Journal ArticleDOI
Molecular Mechanism of the Inhibitory Effect of Aldosterone on Endothelial NO Synthase Activity
Daisuke Nagata,Masao Takahashi,Kuniko Sawai,Tetsuya Tagami,Takeshi Usui,Akira Shimatsu,Yasunobu Hirata,Mitsuhide Naruse +7 more
TL;DR: The results suggest that Aldo inhibits eNOS function through bimodal mechanisms of 5,6,7,8-tetrahydrobiopterin deficiency and protein phosphatase 2A activation and p47phox knockdown.