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Thaddeus Terlumun Gbem
Researcher at Ahmadu Bello University
Publications - 10
Citations - 133
Thaddeus Terlumun Gbem is an academic researcher from Ahmadu Bello University. The author has contributed to research in topics: Trypanosoma & Glycan. The author has an hindex of 6, co-authored 9 publications receiving 105 citations. Previous affiliations of Thaddeus Terlumun Gbem include University of Bremen.
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Journal ArticleDOI
Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense.
Mario Waespy,Thaddeus Terlumun Gbem,Leroy Elenschneider,André-Philippe Jeck,Christopher J. Day,Lauren E. Hartley-Tassell,Nicolai V. Bovin,Joe Tiralongo,Thomas Haselhorst,Sørge Kelm +9 more
TL;DR: Interestingly, terminal mannose residues are not acceptor substrates for TconTS activity, which indicates a different, yet unknown biological function for TConTS-LD, including specific interactions with oligomannose-containing glycans on glycoproteins and GPI anchors found on the surface of the parasite, including the Tcon TS itself.
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Molecular screening of tsetse flies and cattle reveal different Trypanosoma species including T. grayi and T. theileri in northern Cameroon.
Sen Claudine Henriette Ngomtcho,Sen Claudine Henriette Ngomtcho,Judith Sophie Weber,Elisabeth Ngo Bum,Thaddeus Terlumun Gbem,Sørge Kelm,Mbunkah Daniel Achukwi +6 more
TL;DR: This molecular epidemiological study of Trypanosoma species in Northern Cameroon revealed active foci of trypanosomes in Dodeo and Gamba and will serve as a guide for setting the priorities of the government in the control of the disease.
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Biochemical characterization of trans-sialidase TS1 variants from Trypanosoma congolense
Hendrik Koliwer-Brandl,Thaddeus Terlumun Gbem,Mario Waespy,Olga Reichert,Philipp Mandel,Eric Drebitz,Frank Dietz,Sørge Kelm +7 more
TL;DR: The identification and characterization of a trans-sialidase gene family of the African parasite T. congolense has opened new perspectives for investigating the biological role of these enzymes in Nagana and sleeping sickness and have the biotechnological potential to be used for enzymatic modification of sialylated glycoconjugates.
Journal ArticleDOI
Biochemical Diversity in the Trypanosoma congolense Trans-sialidase Family
Thaddeus Terlumun Gbem,Mario Waespy,Bettina Hesse,Frank Dietz,Joel Smith,Gloria Dada Chechet,Jonathan Andrew Nok,Sørge Kelm +7 more
TL;DR: The identification and enzymatic characterisation of the trans-sialidase family in T. congolense will contribute significantly towards the understanding of the roles of these enzymes in the pathogenesis of Animal African Trypanosomiasis.
Journal ArticleDOI
Genetic diversity of trypanosome species in tsetse flies (Glossina spp.) in Nigeria.
Judith Sophie Weber,Sen Claudine Henriette Ngomtcho,Stephen Saikiu Shaida,Gloria Dada Chechet,Thaddeus Terlumun Gbem,Jonathan Andrew Nok,Mohammed Mamman,Daniel Mbunkah Achukwi,Sørge Kelm,Sørge Kelm +9 more
TL;DR: The prevalence of animal pathogenic trypanosomes throughout Nigeria emphasises the role of protected areas as reservoirs for livestock trypanOSomes and the genetic diversity observed within T. vivax and T. grayi populations might be an indication for changing pathogenicity or host range.