Thaleia-Rengina Stathopoulou

TL;DR: Large-animal data support the concept that gene editing approaches may prove clinically useful for the treatment of DMD, and successful CRISPR correction of a dystrophin mutation in dogs increases dystrophicin protein expression in skeletal and heart muscle.

TL;DR: In this article, a cylindrical multielectrode human-sized nerve cuff array was used for cervical vagus nerve selective neuromodulation in anaesthetised sheep.

TL;DR: A detailed fabrication method is presented for silicone-based multiple electrode arrays which can be used for epicortical or neural cuff applications and results position EIT as an effective method to image neural activity.

TL;DR: In this paper, the authors performed neuroanatomical and functional comparison of the mouse, rat, pig, and human splenic nerve using in vivo and ex vivo preparations and found that splenic stimulation was able to promote cardiovascular protection as well as cytokine modulation in a high and a low-dose lipopolysaccharide model, respectively.

TL;DR: Cats with stomatitis showed lower bioavailability and shorter absorption half-life after buccal administration of buprenorphine compared with normal cats in previous studies, and it can be incorporated in their multimodal analgesia plan.