Thambusamy Stalin

TL;DR: In this paper, the effect of solvents, buffer solutions of different pH and β-cyclodextrin (β-CD) on the absorption and fluorescence spectra of 2-aminobenzoic acid (2ABA) have been investigated.

Abstract: Effect of solvents, buffer solutions of different pH and β-cyclodextrin on the absorption and fluorescence spectra of 3-aminobenzoic acid (3ABA) have been investigated. The solid inclusion complex of 3ABA with β-CD is discussed by UV–Vis, fluorimetry, semiempirical quantum calculations (AM1), FT-IR, 1 H NMR and Scanning Electron Microscope (SEM). The thermodynamic parameters (Δ H , Δ G and Δ S ) of the inclusion process are also determined. The experimental results indicated that the inclusion processes is an exothermic and spontaneous. The large Stokes shift emission in solvents with 3ABA are correlated with different solvent polarity scales suggest that, 3ABA molecule is more polar in the S 1 state. Solvent, β-CD studies and excited state dipole moment values confirms that the presence of intramolecular charge transfer (ICT) in 3ABA. Acidity constants for different prototropic equilibria of 3ABA in the S 0 and S 1 states are calculated. β-Cyclodextrin studies shows that 3ABA forms a 1:1 inclusion complex with β-CD. β-CD studies suggest COOH group present in non-polar part and amino group present in hydrophilic part of the β-CD cavity. A mechanism is proposed to explain the inclusion process.

TL;DR: The formation of host-guest inclusion complex of 2,4-dinitrophenol with nano-hydrophobic cavity of β-cyclodextrin in solution phase was studied by UV-visible spectrophotometer and electrochemical method.

TL;DR: The results indicated that the inclusion process of beta-CD with L-tyrosine was an exergonic and spontaneous process.

TL;DR: The in vitro antimicrobial and antibiofilm activity of RFB sensible microorganisms was significantly increased by on inclusion complexation process, which is highly recognized as a successful and useful approach for the application in pharmaceutical field.