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Therese Heinonen
Researcher at Montreal Heart Institute
Publications - 17
Citations - 1379
Therese Heinonen is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Myocardial infarction & Intravascular ultrasound. The author has an hindex of 11, co-authored 16 publications receiving 1293 citations.
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Journal ArticleDOI
Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial.
Jean-Claude Tardif,Jean Grégoire,Philippe L. L’Allier,Reda Ibrahim,Jacques Lespérance,Therese Heinonen,Simon Kouz,Colin Berry,Russell Basser,Marc-André Lavoie,Marie-Claude Guertin,Josep Rodés-Cabau,Efficacy (Erase) Investigators +12 more
TL;DR: Short-term infusions of reconstituted HDL resulted in no significant reductions in percentage change in atheroma volume or nominal change in plaque volume compared with placebo but did result in statistically significant improvement in the plaque characterization index and coronary score on quantitative coronary angiography.
Journal ArticleDOI
Effects of the Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor Avasimibe on Human Atherosclerotic Lesions
Jean-Claude Tardif,Jean Grégoire,Philippe L. L’Allier,Todd J. Anderson,Olivier F. Bertrand,François Reeves,Lawrence M. Title,Fernando Alfonso,Erick Schampaert,Alita Hassan,Richard McLain,Milton L. Pressler,Reda Ibrahim,Jacques Lespérance,John Blue,Therese Heinonen,Josep Rodés-Cabau +16 more
TL;DR: Avasimibe did not favorably alter coronary atherosclerosis as assessed by IVUS, and this ACAT inhibitor also caused a mild increase in LDL cholesterol.
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Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention for Non–ST-Segment Elevation Myocardial Infarction : Results of the SELECT-ACS Trial
Jean-Claude Tardif,Jean Francois Tanguay,Scott S. Wright,Valérie Duchatelle,Thibaut Petroni,Jean Grégoire,Reda Ibrahim,Therese Heinonen,Stephen Robb,Olivier F. Bertrand,Daniel Cournoyer,Dominique Johnson,Jessica Mann,Marie Claude Guertin,Philippe L. L’Allier +14 more
TL;DR: Inclacumab appears to reduce myocardial damage after PCI in patients with non-ST-segment elevation myocardia infarction, and there was no significant difference in adverse events between groups.
Journal ArticleDOI
Quantitative relation between hemodynamic changes during intravenous adenosine infusion and the magnitude of coronary hyperemia: implications for myocardial perfusion imaging.
Rakesh Mishra,Sharmila Dorbala,Giridhar Logsetty,Alita Hassan,Therese Heinonen,Heinrich R. Schelbert,Marcelo F. Di Carli,Rampart Investigators +7 more
TL;DR: Changes in cardiac hemodynamics during intravenous ADO are generally poor predictors of changes in MBF and CVR during peak hyperemia, and, thus, they should not be used to assess the effectiveness of vasodilator stress in myocardial perfusion imaging.
Journal ArticleDOI
The Role of Biomarkers in Decreasing Risk of Cardiac Toxicity after Cancer Therapy.
TL;DR: The purpose of this article is to review the available data to determine the role of biomarkers in decreasing the risk of cardiac toxicity after cancer therapy.