Showing papers in "Journal of the American College of Cardiology in 2013"
TL;DR: In this article, Anderson et al. proposed a new FAHA Chair, Jeffrey L. Anderson, MD, FACC, FAHA, Chair-Elect, Alice K. Jacobs et al., this article and Biykem Bozkurt.
11,386 citations
TL;DR: The 2017-18 FAHA/FACC/FAHA Education and Research Grants will be focused on advancing the profession’s understanding of central nervous system disorders and the management of post-traumatic stress disorder.
4,556 citations
TL;DR: In this article, a new paradigm for heart failure with preserved ejection fraction (HFPEF) development is proposed, which identifies a systemic proinflammatory state induced by comorbidities as the cause of myocardial structural and functional alterations.
2,246 citations
TL;DR: The 2017-18 FAHA/FACC/FAHA Education and Research Grants will be focused on advancing the profession’s understanding of central nervous system disorders and the management of post-traumatic stress disorder.
1,681 citations
TL;DR: Early diagnosis of PAH remains difficult, and screening programs in asymptomatic patients are feasible only in high-risk populations, particularly in patients with systemic sclerosis, for whom recent data suggest that a combination of clinical assessment and pulmonary function testing has a higher predictive value than echocardiography alone.
1,372 citations
TL;DR: FFR derived from CTA was demonstrated as superior to measures of CTA stenosis severity for determination of lesion-specific ischemia, and a review on the scientific principles that underlie this technology is presented.
951 citations
TL;DR: The burden of disease among the elderly due to severe AS is substantial, and the number of candidates for transcatheter aortic valve replacement (TAVR) candidates is estimated to be approximately 290,000.
866 citations
Aix-Marseille University1, Scripps Health2, Gyeongsang National University3, University of Florida4, Columbia University5, National Health Service6, University of Tübingen7, Medical University of Vienna8, Medical University of Graz9, Duke University10, Harvard University11, MedStar Washington Hospital Center12, University of Patras13, University of Florence14, University of Geneva15, University of Freiburg16, Ludwig Maximilian University of Munich17
TL;DR: An updated consensus document reviews the available evidence and proposes cutoff values for high and low on-treatment platelet reactivity to ADP that might be used in future investigations of personalized antiplatelet therapy and proposes a therapeutic window concept for P2Y12 inhibitor therapy.
817 citations
TL;DR: A nonfasting remnant cholesterol increase of 1 mmol/l (39 mg/dl) is associated with a 2.8-fold causal risk for ischemic heart disease, independent of reduced HDL cholesterol, which implies that elevated cholesterol content of triglyceride-rich lipoprotein particles causes ischeMIC heart disease.
796 citations
TL;DR: The STOP AF trial demonstrated that cryoballoon ablation is a safe and effective alternative to antiarrhythmic medication for the treatment of patients with symptomatic paroxysmal AF, for whom at least one antiarrHythmic drug has failed, with risks within accepted standards for ablation therapy.
748 citations
TL;DR: In the real-world, post-approval experience in Europe, patients undergoing the MitraClip therapy are high-risk, elderly patients, mainly affected by functional MR, and in this patient population, the MitRAClip procedure is effective with low rates of hospital mortality and adverse events.
VU University Medical Center1, Stanford University2, University of Texas Southwestern Medical Center3, Temple University4, University of Pennsylvania5, Maastricht University6, Free University of Brussels7, Vanderbilt University8, University of California, Los Angeles9, Virginia Commonwealth University10, Johns Hopkins University11
TL;DR: The authors highlight differences between right and left heart failure and outline key areas of future investigation in right heart pathobiology in PAH.
TL;DR: Colchicine 0.5 mg/day administered in addition to statins and other standard secondary prevention therapies appeared effective for the prevention of cardiovascular events in patients with stable coronary disease.
TL;DR: The increasing prevalence of abdominal obesity, particularly among female adults, highlights the urgency of addressing abdominal obesity as a healthcare priority and the use of therapies for MetS components aligns with favorable trends in their prevalence.
TL;DR: The authors in this paper found that moderate or severe aortic regurgitation was more common with use of the CoreValve (16.0% vs. 9.1%, p = 0.005).
TL;DR: This document is a compilation of the current American College of Cardiology Foundation/American Heart Association practice guideline recommendations for atrial fibrillation (AF) from the “ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation”.
Chinese Ministry of Education1, Harvard University2, University of Hong Kong3, Concord Repatriation General Hospital4, Harbin Medical University5, University of Ulsan6, Yonsei University7, Nippon Medical School8, Nara Medical University9, Iwate Medical University10, Ajou University11, University of Vermont12, Mayo Clinic13, University of Pittsburgh14, St. Jude Medical15, Icahn School of Medicine at Mount Sinai16
TL;DR: Optical coherence tomography is a promising modality for identifying OCT-erosion and OCT-CN in vivo in patients with acute coronary syndrome and is more common in older patients.
TL;DR: Management strategies that when properly implemented may help reduce HF rehospitalizations and include adopting a mechanistic approach to cardiac abnormalities, treating noncardiac comorbidities, increasing utilization of evidence-based therapies, and improving care transitions, monitoring, and disease management are highlighted.
University of Bologna1, Newcastle University2, Baylor College of Medicine3, Michigan State University4, University of Toronto5, Peking Union Medical College6, Vienna General Hospital7, Mayo Clinic8, University of Michigan9, Tufts University10, University of California, San Diego11, Max Planck Society12, St. Vincent's Health System13
TL;DR: The current treatment algorithm may be divided into 3 main areas: 1) general measures, supportive therapy, referral strategy, acute vasoreactivity testing and chronic treatment with calcium channel blockers; 2) initial therapy with approved PAH drugs; and 3) clinical response to the initial therapy, combination therapy, balloon atrial septostomy, and lung transplantation.
TL;DR: Results support the concept that OSA exacerbates the cardiometabolic risk attributed to obesity and the metabolic syndrome, and recognition and treatment of OSA may decrease the cardiovascular risk in obese patients.
TL;DR: In this article, the safety and efficacy of left atrial appendage closure with the Watchman device was evaluated in nonvalvular atrial fibrillation (AF) patients ineligible for warfarin therapy.
Université libre de Bruxelles1, Technion – Israel Institute of Technology2, University of Barcelona3, University of Pittsburgh4, Royal Free Hospital5, Claude Bernard University Lyon 16, University of California, San Francisco7, University of Bologna8, National Institutes of Health9, University of Michigan10, Harvard University11, University of Paris-Sud12, University of Giessen13
TL;DR: In this paper, a change in terminology and a new definition of pulmonary hypertension due to LHD was proposed, and the authors suggest to abandon "out-of-proportion" PH and to distinguish "isolated post-capillary PH" from "post-CAPillary PH with a precapillary component" based on the pressure difference between diastolic pulmonary artery pressure and pulmonary artery wedge pressure.
TL;DR: Endurance exercise and frequent exercise increase the risk of VT/VF, HF, and ARVD/C in desmosomal mutation carriers and support exercise restriction for these patients.
TL;DR: Noncontrast 3DE was the most reproducible technique for LVEF and LV volume measurements over 1 year of follow-up and had the best intra- and inter-observer as well as test-retest variability.
Laval University1, University of British Columbia2, Cedars-Sinai Medical Center3, University of Miami4, Cleveland Clinic5, Columbia University6, University of Catania7, University of Valencia8, University of Toronto9, Erasmus University Rotterdam10, Autonomous University of Madrid11, University of Vigo12, University of Ottawa13, University of A Coruña14, McMaster University15, Washington University in St. Louis16, Emory University17, MedStar Washington Hospital Center18
TL;DR: Symptomatic CO following TAVI was a rare but life-threatening complication that occurred more frequently in women, in patients receiving a balloon-expandable valve, and in those with a previous surgical bioprosthesis, highlighting the importance of anticipating and preventing the occurrence of this complication.
TL;DR: Visceral adiposity is associated with incident cardiovascular disease and cancer after adjustment for clinical risk factors and generalized adiposity, and these findings support the growing appreciation of a pathogenic role of ectopic fat.
University of Giessen1, Max Planck Society2, Technion – Israel Institute of Technology3, University of Barcelona4, Royal Free Hospital5, Claude Bernard University Lyon 16, University of California, San Francisco7, University of Bologna8, National Institutes of Health9, University of Michigan10, Harvard University11, University of Paris-Sud12, Université libre de Bruxelles13
TL;DR: The "severe PH group" includes only a minority of chronic lung disease patients who are suspected of having strong general vascular abnormalities accompanying the parenchymal disease and with evidence of an exhausted circulatory reserve rather than an exhausted ventilatory reserve underlying the limitation of exercise capacity.
TL;DR: In this article, the authors identified the risk of sudden cardiac death associated with obstructive sleep apnea (OSA) and proposed a risk stratification for SCD, a major cause of mortality.
University of Texas Health Science Center at Houston1, University of Texas at Austin2, University of Missouri–Kansas City3, University of Ottawa4, Hochschule Hannover5, Ochsner Medical Center6, Cleveland Clinic7, Harvard University8, Washington University in St. Louis9, University of Zurich10, VU University Medical Center11, University of Turku12, University of California, Los Angeles13, Ludwig Maximilian University of Munich14, Wayne State University15, University of Maryland, Baltimore16, Icahn School of Medicine at Mount Sinai17
TL;DR: The basic concepts that hold true for whatever technology measures coronary physiology directly and reliably are clarified, here focusing on positron emission tomography and its interplay with intracoronary measurements.
TL;DR: Combined treatment with enalapril and carvedilol may prevent LVSD in patients with malignant hemopathies treated with intensive chemotherapy, and the clinical relevance of this strategy should be confirmed in larger studies.