T
Thomas Benner
Researcher at Harvard University
Publications - 73
Citations - 11228
Thomas Benner is an academic researcher from Harvard University. The author has contributed to research in topics: Diffusion MRI & Stroke. The author has an hindex of 46, co-authored 73 publications receiving 10287 citations. Previous affiliations of Thomas Benner include Massachusetts Institute of Technology & University of California, San Diego.
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Journal ArticleDOI
AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients
Tracy T. Batchelor,A. Gregory Sorensen,A. Gregory Sorensen,Emmanuelle di Tomaso,Wei Ting Zhang,Wei Ting Zhang,Dan G. Duda,Kenneth S. Cohen,Kevin R. Kozak,Daniel P. Cahill,Poe Jou Chen,Poe Jou Chen,Mingwang Zhu,Mingwang Zhu,Marek Ancukiewicz,Maciej M. Mrugala,Scott R. Plotkin,Jan Drappatz,David N. Louis,Percy Ivy,David T. Scadden,Thomas Benner,Jay S. Loeffler,Patrick Y. Wen,Rakesh K. Jain +24 more
TL;DR: This study provides insight into different mechanisms of action of this class of drugs in recurrent glioblastoma patients and suggests that the timing of combination therapy may be critical for optimizing activity against this tumor.
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Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers
Van J. Wedeen,Ruopeng Wang,Jeremy D. Schmahmann,Thomas Benner,Wen-Yih Isaac Tseng,Guangping Dai,Deepak N. Pandya,Patric Hagmann,Patric Hagmann,Helen D'Arceuil,A. J. de Crespigny +10 more
TL;DR: Findings indicate that DSI tractography is able to image crossing fibers in neural tissue, an essential step toward non-invasive imaging of connectional neuroanatomy.
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Brain Morphometry with Multiecho MPRAGE
TL;DR: Since acquisition time is the same for MEMPR as for MPRAGE, and it has better distortion properties and additional T2* information, MEMPR is recommended for morphometry studies.
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Phase II Study of Cediranib, an Oral Pan–Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent Glioblastoma
Tracy T. Batchelor,Dan G. Duda,Emmanuelle di Tomaso,Marek Ancukiewicz,Scott R. Plotkin,Elizabeth R. Gerstner,April F. Eichler,Jan Drappatz,Fred H. Hochberg,Thomas Benner,David N. Louis,Kenneth S. Cohen,Houng Chea,Alexis Exarhopoulos,Jay S. Loeffler,Marsha A. Moses,Percy Ivy,A. Gregory Sorensen,Patrick Y. Wen,Rakesh K. Jain +19 more
TL;DR: Cediranib monotherapy for recurrent glioblastoma is associated with encouraging proportions of radiographic response, 6-month progression-free survival, and a steroid-sparing effect with manageable toxicity.
Journal ArticleDOI
Preoperative and intraoperative diffusion tensor imaging-based fiber tracking in glioma surgery.
Christopher Nimsky,Oliver Ganslandt,Peter Hastreiter,Ruopeng Wang,Thomas Benner,A. Gregory Sorensen,Rudolf Fahlbusch +6 more
TL;DR: Comparing preoperative and intraoperative fiber tracking visualizes a marked shifting and deformation of major white matter tracts because of tumor removal that emphasizes the need for an intraoperative update of navigation systems during resection of deep-seated tumor portions near eloquent brain areas.