T
Thomas C. Britton
Researcher at Harvard University
Publications - 10
Citations - 1350
Thomas C. Britton is an academic researcher from Harvard University. The author has contributed to research in topics: Enantioselective synthesis & Amino acid. The author has an hindex of 7, co-authored 10 publications receiving 1326 citations.
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Journal ArticleDOI
The asymmetric synthesis of .alpha.-amino acids. Electrophilic azidation of chiral imide enolates, a practical approach to the synthesis of (R)- and (S)-.alpha.-azido carboxylic acids
Journal ArticleDOI
Contrasteric carboximide hydrolysis with lithium hydroperoxide
TL;DR: In this article, the use of lithium hydroperoxide for the highly regioselective hydrolysis of a range of carboximides is described, and several cases are provided where the reagent exhibited dramatically different than the complementary reactions with hydroxide.
Journal ArticleDOI
Stereoselective amination of chiral enolates. A new approach to the asymmetric synthesis of .alpha.-hydrazino and .alpha.-amino acid derivatives
TL;DR: In this article, the electrophile d'enolates chiraux derives d'acyl-3 oxazolidones par l'azoformiate de di-t-butyle permet la synthese d'α-hydrazino-and α-aminoacides.
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The asymmetric synthesis of α-amino and α-hydrazino acid derivatives via the stereoselective amination of chiral enolates with azodicarboxylate esters
TL;DR: In this article, the utility of azodicarboxylate esters as (+)NH2 and (+) NH-NH2 synthons in highly diastereoselective reactions with chiral carboximide-derived enolates has been demonstrated.