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Thomas C. Cantley

Researcher at University of Missouri

Publications -  9
Citations -  1160

Thomas C. Cantley is an academic researcher from University of Missouri. The author has contributed to research in topics: In vitro maturation & Blastocyst. The author has an hindex of 9, co-authored 9 publications receiving 1136 citations.

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Synchronization of meiosis in porcine oocytes by exposure to dibutyryl cyclic adenosine monophosphate improves developmental competence following in vitro fertilization.

TL;DR: Exposure of COCs to dbcAMP for the first 20 h of culture for maturation increases the homogeneity of oocyte nuclear maturation and improves the efficiency of in vitro production of swine embryos.
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Use of low-salt culture medium for in vitro maturation of porcine oocytes is associated with elevated oocyte glutathione levels and enhanced male pronuclear formation after in vitro fertilization.

TL;DR: In this paper, the effects of sodium chloride (NaCl) in Whitten's medium on intracellular glutathione concentration and on cytoplasmic maturation, as determined by monospermic penetration and male pronuclear formation of porcine oocytes, were examined.
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Coculture with follicular shell pieces can enhance the developmental competence of pig oocytes after in vitro fertilization: relevance to intracellular glutathione.

TL;DR: The authors examined the effect of follicular shell pieces (FSP) during in vitro maturation (IVM) of porcine oocytes on 1) in vitro fertilization (IVF) parameters, 2) subsequent embryo development, 3) oocyte glutathione (GSH) concentration, and 4) viability after embryo transfer.
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Presence of epidermal growth factor during in vitro maturation of pig oocytes and embryo culture can modulate blastocyst development after in vitro fertilization.

TL;DR: The results show that EGF at certain concentrations in IVM medium can influence the developmental competence of oocytes, however, addition of EGF during the culture of pig embryos derived from oocytes matured in the presence of E GF is without effect.
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In vitro development of in vitro-matured porcine oocytes following chemical activation or in vitro fertilization.

TL;DR: Results indicate that culture in modified Whitten's medium as compared with a standard medium improves cytoplasmic maturation of porcine oocytes as evaluated by intracellular glutathione content, pronuclear formation, and development in vitro after artificial activation or fertilization in vitro.